| coagulable | Capable of being coagulated or clotted. (05 Mar 2000) |
|---|---|
| coagulant | 1. An agent that causes, stimulates, or accelerates coagulation, especially with reference to blood. Synonym: coagulative. (05 Mar 2000) |
| coagulants | Exogenous substances used to promote blood coagulation. The endogenous blood coagulation factors are considered to be coagulants only when administered as drugs. (12 Dec 1998) |
| coagulase | Any bacterial component or product which causes coagulation in plasma containing an anticoagulant such as citrate, heparin or oxalate. Coagulases are produced by certain staphylococci and by yersinia pestis. Staphylococci produce two types of coagulase: staphylocoagulase, a free coagulase that produces true clotting of plasma, and staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen. (12 Dec 1998) |
| coagulate | 1. To convert a fluid or a substance in solution into a solid or gel. 2. To clot; to curdle; to change from a liquid to a solid or gel. Origin: L. Coagulo, pp. -atus, to curdle (05 Mar 2000) |
| coagulation | 1. <haematology> The process of clot formation. 2. <chemistry> The solidification of a sol into a gelatinous mass, an alteration of a disperse phase or of a dissolved solid which causes the separation of the system into a liquid phase and an insoluble mass called the clot or curd. Coagulation is usually irreversible. 3. <surgery> The disruption of tissue by physical means to form an amorphous residuum, as in electrocoagulation and photocoagulation. Origin: L. Coagulatio (18 Nov 1997) |
| coagulation factor | <haematology> Group of plasma protein substances (Factor I-XIII) contained in the plasma, which act in concert to bring about blood coagulation. Many of the factors contain EGF like domains. (29 Sep 1997) |
| coagulation factor XI | <haematology> A plasma serine protease with an apple domain. (18 Nov 1997) |
| coagulation necrosis | A type of necrosis in which the affected cells or tissue are converted into a dry, dull, fairly homogeneous eosinophilic mass without nuclear staining, as a result of the coagulation of protein as occurs in an infarct; microscopically, the necrotic process involves chiefly the cells, and remnants of histologic elements (e.g., elastin, collagen, muscle fibres) may be recognizable, as well as "ghosts" of cells and portions of cell membranes; may be caused by heat, ischemia, and other agents that destroy tissue, including enzymes that would continue to alter the devitalised cellular substance. (05 Mar 2000) |
| coagulation profile | A test which measures the speed of blood coagulation at different steps of the coagulation pathway. (27 Sep 1997) |
| coagulation time | The time required for blood to coagulate; prolonged in haemophilia and in the presence of obstructive jaundice, some anaemias and leukaemias, and some of the infectious diseases. Synonym: clotting time. (05 Mar 2000) |
| coagulation vitamin | An obsolete term for vitamin K. (05 Mar 2000) |
| coagulative | Causing coagulation. Synonym: coagulant. (05 Mar 2000) |
| coagulopathy | <haematology> A defect in the blood clotting mechanism. Examples include haemophilia, drug-induced clotting disorder, thrombocytopenia and Von Willebrand's disease. Origin: Gr. Pathos = disease (27 Sep 1997) |
| coagulum | A clot or a curd; a soft, nonrigid, insoluble mass formed when a sol undergoes coagulation. Origin: L. A means of coagulating, rennet (05 Mar 2000) |