| cefotetan | <chemical> A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infections and to date no severe side effects have been noted. Pharmacological action: cephamycins. Chemical name: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl)carbonyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, (6R-(6alpha,7alpha))- (12 Dec 1998) |
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| cefotetan disodium | C17H15N7Na2O8S4;a broad spectrum cephalosporin antibiotic. (05 Mar 2000) |
| cefotiam | <chemical> A cephalosporin antibiotic that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It is the drug of choice for biliary tract infections and is a safe drug for perinatal infections. Pharmacological action: cephalosporins. Chemical name: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)acetyl)amino)-3-(((1-(2-(dimethylamino)ethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, (6R-trans)- (12 Dec 1998) |
| cefoxitin | <chemical> Semisynthetic cephamycin antibiotic resistant to beta-lactamase. Pharmacological action: cephamycins. Chemical name: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-methoxy-8-oxo-7-((2-thienylacetyl)amino)-, (6R-cis)- (12 Dec 1998) |
| cefoxitin sodium | A semisynthetic antibiotic derived from cephamycin C but structurally and pharmacologically similar to the cephalosporins; used by injection. (05 Mar 2000) |
| cefsulodin | <chemical> A pyridinium-substituted semisynthetic, broad-spectrum antibacterial used especially for pseudomonas infections in debilitated patients. Pharmacological action: cephalosporins. Chemical name: Pyridinium, 4-(aminocarbonyl)-1-((2-carboxy-8-oxo-7-((phenylsulfoacetyl)amino)-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-, inner salt, monosodium salt, (6R-(6alpha,7beta(R*)))- (12 Dec 1998) |
| ceftazidime | <chemical> Semisynthetic, broad-spectrum antibacterial derived from cephaloridine and used especially for pseudomonas and other gram-negative infections in debilitated patients. Pharmacological action: cephalosporins. Chemical name: Pyridinium, 1-((7-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-, inner salt, pentahydrate, (6R-(6alpha,7beta(Z)))- (12 Dec 1998) |
| ceftazidime sodium | C22H21N6NaO7S2;a cephalosporin antibiotic especially effective against enterobacteria and species of Pseudomonas. (05 Mar 2000) |
| ceftizoxime | <chemical> A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with haematologic disorders. Pharmacological action: cephalosporins. Chemical name: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-, (6R-(6alpha,7beta(Z)))- (12 Dec 1998) |
| ceftizoxime sodium | C13H12N5NaO5S2;a broad spectrum cephalosporin antibiotic similar to cefotaxime sodium. (05 Mar 2000) |
| ceftriaxone | <chemical> Broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to usually inaccessible infections, including those involving the meninges, eyes, inner ears, and urinary tract. Pharmacological action: cephalosporins. Chemical name: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio)methyl)-, (6R-(6alpha,7beta(Z)))- (12 Dec 1998) |
| ceftriaxone disodium | C18H16N8Na2O7S3;a semisynthetic parenteral cephalosporin antibiotic. (05 Mar 2000) |
| cefuroxime | <chemical> Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhoea, and haemophilus. Pharmacological action: cephalosporins. Chemical name: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-((2-furanyl(methoxyimino)acetyl)amino)-8-oxo-, (6R-(6alpha,7beta(Z)))- (12 Dec 1998) |
| cefuroxime axetil esterase | <enzyme> Catalyses the hydrolysis of cefuroxime axetil to cefuroxime; also acts (slowly) on p-nitrophenyl acetate and alpha-naphthyl acetate Registry number: EC 3.1.1.- (26 Jun 1999) |