| CD4 immunoadhesins | <immunology> Chimeric molecules resulting from the fusion of recombinant soluble CD4 to the fc portion of immunoglobulins. These have potential use in the therapy of aids since they possess both the gp120-binding and HIV-blocking properties of rCD4 as well as the long plasma half-life and fc receptor-binding functions of immunoglobulin. (12 Dec 1998) |
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| CD4 lymphocyte | A specific type of lymphocyte, derived from the thymus gland, that plays an important role in cellular immunity. T4 lymphocytes (CD4 cells) are decreased (absolute counts less than 200) in patients with AIDS resulting in compromised immune function. (27 Sep 1997) |
| CD4-positive T-lymphocytes | A critical subpopulation of regulatory T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the t4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes, which includes both the helper-inducer (T-lymphocytes, helper-inducer) and suppressor-inducer (T-lymphocytes, suppressor-inducer) T-cells. (12 Dec 1998) |
| t-lymphocytopenia, idiopathic CD4-positive | Reproducible depletion of CD4+ lymphocytes below 300 per cubic millimeter in the absence of HIV infection or other known causes of immunodeficiency. This is a rare, heterogeneous syndrome and does not appear to be caused by a transmissible agent. (12 Dec 1998) |
| absolute eosinophil count | <haematology, investigation> A measurement (cells per microlitre) of the number of eosinophils in a blood specimen. This measurement is useful in the evaluation of autoimmune disease, allergies, eczema, leukaemia, asthma and hay fever. Normal absolute eosinophil counts are less than 350 cells/mcl (microlitre). (27 Sep 1997) |
| Addis count | A quantitative enumeration of the red blood count, white blood count, and casts in a 12-hr urine specimen; used to follow the progress of known renal disease. (05 Mar 2000) |
| Arneth count | The percentage distribution of polymorphonuclear neutrophils, based on the number of lobes in the nuclei (from 1 to 5). See: Arneth index. (05 Mar 2000) |
| blood count | <haematology, investigation> The determination of the proper number of red blood cells, white blood cells and platelets are present in the patients blood. Acronym: FBC (16 Dec 1997) |
| viable count | Measurement of the concentration of live cells in a microbial population. (09 Oct 1997) |
| reticulocyte count | Determination of the number of reticulocytes in a measured volume of blood. Values for reticulocytes are expressed as a percentage of the erythrocyte count or in the form of a so-called "corrected" reticulocyte "index". An increase in circulating reticulocytes, often referred to as reticulocytosis, is among the simplest and most reliable signs of accelerated erythrocyte production. Reticulocytosis, or an increased reticulocyte count, occurs during active blood regeneration (stimulation of red bone marrow) and in certain anaemias, particularly congenital haemolytic anaemia. (12 Dec 1998) |
| colony count, microbial | Enumeration by direct count of viable, isolated bacterial or fungal cells or spores capable of growth on solid culture media. Each colony (i.e., microbial colony-forming unit) represents the progeny of a single cell in the original inoculum. The method is used routinely by environmental microbiologists for quantifying organisms in air, food, and water; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing. (12 Dec 1998) |
| complete blood count | <haematology, investigation> The number of red blood cells, white blood cells and platelets are present in the patients sample of blood is determined. most common test done on the blood. Acronym: CBC Synonym: full blood count. (16 Mar 1998) |
| platelet count | <haematology> The number of platelets per cubic millimetre of blood. The normal range is 150,000-400,000 platelets per cubic mm. Platelet counts under 10,000 per cubic millimetre place the patient at risk for spontaneous haemorrhage. Platelets are produced in the bone marrow in increased quantities in response to stress. (27 Sep 1997) |
| count | 1. A reckoning, enumeration, or accounting. 2. To enumerate or score. (05 Mar 2000) |
| count density | The number of counted events recorded in scintigraphy per square centimeter or per square inch of imaged area. Synonym: count density. (05 Mar 2000) |