| carbamate kinase | A phosphotransferase catalyzing the reaction of carbamoyl phosphate and ADP to form ATP, NH3, and CO2. (05 Mar 2000) |
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| carbamates | Salts or esters of carbamic acid. They contain the general formula nh2-coo-. (12 Dec 1998) |
| carbamazepine | <drug> This tricyclic prescription drug is used to treat convulsions, epilepsy and manic episodes. (09 Oct 1997) |
| carbamic acid | A hypothetical acid, NH2-COOH, forming carbamates; the acyl radical is carbamoyl. (05 Mar 2000) |
| carbamide | An obsolete term for urea. (05 Mar 2000) |
| carbamino compound | Any carbamic acid derivative formed by the combination of carbon dioxide with a free amino group to form an N-carboxy group, -NH-COOH, as in haemoglobin forming carbaminohemoglobin. (05 Mar 2000) |
| carbaminohemoglobin | Carbon dioxide bound to haemoglobin by means of a reactive amino group on the latter, i.e., Hb-NHCOOH; approximately 20% of the total content of carbon dioxide in blood is combined with haemoglobin in this manner. Synonym: carbhemoglobin, carbohemoglobin. (05 Mar 2000) |
| carbamoate | 1. A salt or ester of carbamic acid forming the basis of urethane hypnotics. 2. A group of cholinesterase inhibiting insecticides resembling organophosphates; the most frequent carbamate is carbaril. Synonym: carbamoate, carbaril. (05 Mar 2000) |
| carbamoyl | The acyl radical, NH2-CO-, the transfer of which plays an important role in certain biochemical reactions; e.g., in the urea cycle, via carbamoyl phosphate. (05 Mar 2000) |
| carbamoyl phosphate | H2NCO-OPO32-;a reactive intermediate capable of transferring its carbamoyl group (H2NCO-) to an acceptor molecule, forming citrulline from ornithine in the urea cycle, and ureidosuccinic acid from aspartic acid in pyrimidine ring formation. (05 Mar 2000) |
| carbamoyl phosphate synthetase | A phosphotransferase catalyzing the formation of carbamoyl phosphate. There are two significant isozymes. Carbomoyl phosphate synthetase I is a mitochondrial enzyme that catalyses the reaction of 2ATP, NH3, CO2, and H2O to carbamoyl phosphate, 2ADP, and Pi. It is activated by N-acetylglutamate and participates in urea biosynthesis. A deficiency of carbamoyl phosphate synthetase I can result in hyperammonaemia. Carbamoyl phosphate synthetase II is a cytosolic enzyme that, under physiological conditions, uses l-glutamine as the nitrogen source (producing l-glutamate) instead of NH3, is not activated by N-acetylglutamate, and is found in pyrimidine biosynthesis. (05 Mar 2000) |
| carbamoyl-phosphate synthase (ammonia) | <enzyme> An enzyme that catalyses the formation of carbamoyl phosphate from ATP, carbon dioxide, and ammonia. This enzyme is specific for arginine biosynthesis or the urea cycle. Chemical name: Carbon dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating) Registry number: EC 6.3.4.16 (12 Dec 1998) |
| carbamoyl-phosphate synthase (glutamine-hydrolyzing) | <enzyme> An enzyme that catalyses the formation of carbamoyl phosphate from ATP, carbon dioxide, and glutamine. This enzyme is important in the de novo biosynthesis of pyrimidines. Chemical name: Carbon dioxide:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) Registry number: EC 6.3.5.5 (12 Dec 1998) |
| carbamoylaspartate dehydrase | dihydro-orotase |
| carbamoylation | Transfer of the carbamoyl from a carbamoyl-containing molecule (e.g., carbamoyl phosphate) to an acceptor moiety such as an amino group. (05 Mar 2000) |