| alpha blocking | The attenuation of the occipital alpha rhythm (8-14 Hz brain waves as seen on an electroencephalogram), produced by opening the eyes or by intense mental concentration. (05 Mar 2000) |
|---|---|
| antibodies, blocking | Antibodies that inhibit the reaction between antigen and other antibodies or sensitised T-lymphocytes (e.g., antibodies of the IgG class that compete with IgE antibodies for antigen, thereby blocking an allergic response). Blocking antibodies that bind tumours and prevent destruction of tumour cells by cytotoxic T-lymphocytes have also been called enhancing antibodies. (12 Dec 1998) |
| blocking | 1. Obstructing; arresting of passage, conduction, or transmission. 2. In psychoanalysis, a sudden break in free association occurring when a painful subject or repressed complex is touched. 3. Sudden cessation of thoughts and speech, which may indicate the presence of a severe thought disorder or a psychosis. (05 Mar 2000) |
| blocking activity | The repression or elimination of electrical activity in the brain by the arrival of a sensory stimulus. (05 Mar 2000) |
| blocking agent | A class of drugs that inhibit (block) a biologic activity or process, such as axonal conduction or transmission, or ions across a cell membrane; frequently called "blockers." (05 Mar 2000) |
| blocking antibody | An antibody used in a reaction to prevent some other reaction taking place, for example one antibody competing with another for a cell surface receptor. See: desensitisation. (18 Nov 1997) |
| ganglionic blocking agent | An agent that impairs the passage of impulses in autonomic ganglia. (05 Mar 2000) |
| Rh blocking test | A test for nonagglutinating Rh antibodies: an Rh agglutination test is first carried out; if the test for Rh agglutinins is negative, then 1 drop of anti-Rho agglutinating serum of moderate titre is mixed with the patient's serum containing Rh-positive test cells; if after incubating for from 1 to 2 hr at 37캜 no agglutination occurs, Rho-blocking antibodies are assumed to be present in the patient's serum. (05 Mar 2000) |
| slow channel-blocking agent | calcium channel-blocking agent |
| neuromuscular blocking agent | A group of drugs that prevent motor nerve endings from exciting skeletal muscle. They act either by competing for the neurotransmitter, acetylcholine, (like D-tubocurarine, mivacurium and pancuronium), or by first stimulating the postjunctional muscle membrane and subsequently desensitizing the muscle endplates to the acetylcholine (like succinylcholine or decamethonium); used in surgery to produce paralysis and facilitate manipulation of muscles. (05 Mar 2000) |
| nondepolarising neuromuscular blocking agent | A compound that paralyzes skeletal muscle primarily by inhibiting transmission of nerve impulses at the neuromuscular junction rather than by affecting the membrane potention of motor endplate or muscle fibres. (05 Mar 2000) |
| androst-5-ene-3 beta,17 beta-diol | <chemical> An adrenal-derived oestrogenic metabolite of dhea. Evidence exist for its use as an endocrine regulator of immune response. Pharmacological action: anabolic steroids. Chemical name: Androst-5-ene-3,17-diol, (3beta,17beta)- (12 Dec 1998) |
| beta-1,3-galactosyl-0-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase | <enzyme> Capable of adding a glcnac residue to g1cnacman(3)g1cnac; from mung bean seedlings Registry number: EC 2.4.1.146 Synonym: n-acetylglucosaminyltransferase II, gal3-(glcnac6)galnac-mucin (glcnac--gal)3-glcnactransferase (26 Jun 1999) |
| beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-acetylglucosaminyl transferase | <enzyme> With EC 2.4.1.148 this is called beta6-glcnac-transferase b Registry number: EC 2.4.1.102 Synonym: gal3-galnac-mucin-6-glcnac transferase, udp-glcnac-gal1-3galnac-r-(glcnac to galnac)-beta1-6glcnac transferase, core 2 glcnac transferase, core 2-n-acetylglucosaminyltransferase, core 2 beta6-gn-t (26 Jun 1999) |
| beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase | <enzyme> Induced in preneoplastic stage of liver carcinogenesis promoted by orotic acid in rats; adds "bisecting n-acetylglucosaminyl residue in beta 1,4 linkage to the beta-linked mannose of the core of asparagine-linked oligosaccharides Registry number: EC 2.4.1.144 Synonym: n-acetylglucosaminyltransferase III, udpgnac-glycopeptide beta4-n-acetylglucosaminyl transferase III, udpgnac-magtransferase III, udp-n-acetylglucosamine-beta-d-mannoside beta-1,4-n-acetylglucosaminyltransferase III (26 Jun 1999) |