| 영문 | rheumatic heart disease | 한글 | 류마티스심장병 |
|---|---|---|---|
| 설명 | 사슬알균감염 후 생기는 심장판막병이다. 원인은 A군 -용혈사슬알에 의한 인두염후 일종의 면역반응으로 발병한다. 진단은 존의 기준에 의한다. (1) 주요기준은 관절염 심장염(심장비대, 심장잡음, 심장기능상실 등) 무도증: 무당이 춤을 추는 것 같은 행동의 발작증세. 연변홍반: 빨간 테두리를 가진 피부병변은 피하결절(subcutaneous nodule): 피부 밑에 생긴 결절, (2)참고 기준은 열, 관절통, EKG상 PR연장: 심전도 소견 급성기 반응물질(예: ESR, CRP)의 상승, 류마티스열 치료는 페니실린으로 치료하고 심장의 후유증 또한 페니실린으로 예방한다. |
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| 영문 | chronic obstructive pulmonary disease | 한글 | 만성폐쇄폐병 |
|---|---|---|---|
| 설명 | 만성적으로 기도의 폐쇄를 가져오는 병을 이르는 말. 대개 만성기관지염, 기관지 천식, 폐기종의 3가지 병을 말한다. 만성기관지염이란 기관지의 만성염증을 말한다. 기관지의 염증으로 인해서 기관지의 점막에 부종이 생기고 이로 인해서 기관지의 내경이 좁아져서 기도의 폐쇄를 가져온다. 대개 흡연과 밀접한 연관을 가지며, 호흡곤란, 기침, 그리고 가래(대개 색이 푸르고 점도가 높은 가래)가 증상으로 나타난다. 폐기종은 기관지의 벽을 지지하는 조직의 파괴에 의해서 기관지가 제 모양을 갖추지 못하고 무너지게 되어 기도의 폐쇄가 일어나는 병이다. 즉 기관지가 관 모양으로 팽팽하게 펴지는 것을 지지하는 조직의 파괴에 의해서 관모양으로 펴지지 못해 결국은 폐포내에 공기가 차고 폐포벽이 파열되고 기관지가 좁아지게 되는 병을 말한다. 기관지천식이란 여러 가지 자극에 대해서 기관지가 과민한 반응을 보여서 생기는 기관지의 가역적인 폐쇄를 의미한다. 즉 정상인에게서는 기관지의 폐쇄를 보이지 않는 자극에 대해서 기관지의 폐쇄가 생기고 그 자극이 없을 경우에는 기관지의 폐쇄가 없어지는 병을 말한다. |
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| 영문 | Buerger disease | 한글 | 버거병 |
|---|---|---|---|
| 설명 | 말초 동맥과 정맥에 염증을 일으키는 병. 청장년층의 남자에게 잘 걸리는 다리 동맥에 생기는 병으로 동맥이 막히고 통증 때문에 발을 절기도 하는데 원인은 알려져 있지 않다. 병명은 이 병을 최초로 상세하게 보고한 미국의 의사 L. 버거(1879~1943)의 이름에서 연유한다. 동양인에게 많은 병으로, 대부분 젊은 남성, 특히 장년기 남성에게서 나타난다. 원인은 알 수 없으나 흡연이 병의 악화를 초래한다. 사지의 동맥과 정맥에 염증이 일어나 혈전이 생기면 내강을 막아 혈액이 흐르지 못하게 되어 그 앞의 말초조직이 괴사에 빠지거나 손발이 차갑고, 손가락-발가락이 보라색 또는 검은색으로 변한다. 또, 이 증세가 계속되는 동안 손발가락에 통증이 일어나고 궤양이 발생한다. 치료는 증세의 정도와 폐색된 혈관의 부위에 따라 연고를 바르거나 혈관확장제-순환개선제-혈소판응집억제제를 사용하나, 어떤 치료도 효과가 없을 경우 손발가락의 소절단, 드물게는 무릎 이하의 대절단을 해야 한다. 일반적으로 이 병의 예후는 양호하여 혈류가 회복되고 궤양만 치료되면 재발이 적다. |
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| 영문 | Behcet disease | 한글 | 베체트병 |
|---|---|---|---|
| 설명 | 심한 포도막염, 망막혈관염, 시각신경위축, 구강-성기의 아프타성 궤양, 광범위한 혈관염의 징후와 증상을 나타낸다. 원인불명의 희귀한 병으로 젊은 남자에게 잘 발생한다. |
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| 영문 | congenital heart disease | 한글 | 선천심장병 |
|---|---|---|---|
| 설명 | 선천적으로 심장의 구조에 이상이 있는 병. |
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| PD | Doctor of Pharmacy; Dublin Pharmacopoeia; interpupillary distance; Paget disease; pancreatic duct; p... |
|---|---|
| RD | radial deviation; radiology department; rate difference; Raynaud disease; reaction of degeneration; ... |
| CHD | Chediak-Higashi disease; childhood disease; chronic hemodialysis; congenital or congestive heart dis... |
| CRD | carbohydrate-recognition domain; chronic renal disease; chronic respiratory disease; child restraint... |
| MAIN | medication-induced, autoimmune, infectious, and neoplastic [diseases associated with antiphospholipi... |
| anaemia | <haematology> Too few red blood cells in the bloodstream, resulting in insufficient oxygen to tissues and organs. Origin: Gr. Haima = blood (16 Dec 1997) |
|---|---|
| anaemia, aplastic | A form of anaemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements. (12 Dec 1998) |
| anaemia, Cooley's | Better known today as thalassaemia (or as beta thalassaemia or thalassaemia major).The clinical picture of this important type of anaemia was first described in 1925 by the paediatrician Thomas Benton Cooley. Another name for the disease is Mediterranean anaemia. The name thalassaemia was coined by the Nobel Prise winning pathologist George Whipple and the professor of paediatrics Wm Bradford at Univ. Of Rochester because thalassa in Greek means the sea (like the Mediterrranean Sea) + -aemia means in the blood so thalassaemia means sea in the blood. Thalassaemia is not just one disease. It is a complex contingent of genetic (inherited) disorders all of which involve underproduction of haemoglobin, the indispensable molecule in red blood cells that carries oxygen. The globin part of normal adult haemoglobin is made up of 2 alpha and 2 beta polypeptide chains. In beta thalassaemia, there is a mutation (change) in both beta globin chains leading to underproduction (or absence) of beta chains, underproduction of haemoglobin, and profound anaemia. The gene for beta thalassaemia is relatively frequent in people of Mediterranean origin (for example, from Italy and Greece). Children with this disease inherit one gene for it from each parent. The parents are carriers (heterozygotes) with just one thalassaemia gene, are said to have thalassaemia minor, and are essentially normal. Their children affected with beta thalassaemia seem entirely normal at birth because at birth we still have predominantly foetal haemoglobin which does not contain beta chains. The anaemia surfaces in the first few months after birth and becomes progressively more severe leading to pallor and easy fatiguability, failure to thrive (grow), bouts of fever (due to infections) and diarrhoea. Treatment based on blood transfusions is helpful but not curative. Gene therapy will, it is hoped, be applicable to this disease. (12 Dec 1998) |
| anaemia, dyserythropoietic, congenital | A familial disorder characterised by anaemia with multinuclear erythroblasts, karyorrhexis, asynchrony of nuclear and cytoplasmic maturation, and various nuclear abnormalities of bone marrow erythrocyte precursors. Type II is the most common of the 3 types of congenital dyserythropoietic anaemia; it is often referred to as hempas, based on the hereditary erythroblast multinuclearity with positive acidified serum test. (12 Dec 1998) |
| anaemia gravis | <haematology> This form of anaemia occurs when the bone marrow ceases sufficient red and white blood cell production. It may be induced by exposures to high levels of toxic chemicals, radiation and certain drugs. It is generally unresponsive to specific therapy, often accompanied by granulocytopenia and thrombocytopenia, in which the bone marrow may not necessarily be hypocellular or hypoplastic but fails to produce adequate numbers of peripheral blood elements. The term actually is all inclusive and most probably encompasses several clinical syndromes. Origin: Gr. Haima = blood (29 Sep 1997) |
| anaemia, haemolytic | Anaemia due to decreased life span of erythrocytes. (12 Dec 1998) |
| anaemia, haemolytic, autoimmune | Acquired haemolytic anaemia due to the presence of autoantibodies which agglutinate or lyse the patient's own red cells. (12 Dec 1998) |
| anaemia, haemolytic, congenital | Haemolytic anaemia due to various intrinsic defects of the erythrocyte. (12 Dec 1998) |
| anaemia, haemolytic, congenital nonspherocytic | Any one of a group of congenital haemolytic anaemias in which there is no abnormal haemoglobin or spherocytosis and in which there is a defect of glycolysis in the erythrocyte. In some cases, pyruvate kinase deficiency has been demonstrated; in other cases, glucose-6-phosphate dehydrogenase deficiency has been demonstrated. (12 Dec 1998) |
| anaemia, hypochromic | Anaemia characterised by a decrease in the ratio of the weight of haemoglobin to the volume of the erythrocyte, i.e., the mean corpuscular haemoglobin concentration is less than normal. The individual cells contain less haemoglobin than they could have under optimal conditions. Hypochromic anaemia may be caused by iron deficiency from a low iron intake, diminished iron absorption, or excessive iron loss. It can also be caused by infections or other diseases, therapeutic drugs, lead poisoning, and other conditions. (12 Dec 1998) |
| anaemia, iron deficiency | Deficiency of iron results in anaemia because iron is necessary to make haemoglobin, the key molecule in red blood cells responsible for the transport of oxygen. In iron deficiency anaemia, the red cells are unusally small (microcytic) and pale (hypochromic). Characteristic features of iron deficiency anaemia in children include failure to thrive (grow) and increased infections. The treatment of iron deficiency anaemia, whether it be in children or adults, is with iron and iron-containing foods. Food sources of iron include meat, poultry, eggs, vegetables and cereals (especially those fortified with iron). According to the National Academy of Sciences, the Recommended Dietary Allowances of iron are 15 milligrams per day for women and 10 milligrams per day for men. Anaemia characterised by low or absent iron stores, low serum iron concentration, elevated free erythrocyte porphorin, low transferrin saturation, elevated transferrin, low serum ferritin, low haemoglobin concentration or haematocrit, and hypochromic microcytic red blood cells. Symptoms may include pallor, angular stomatitis and other oral lesions, gastrointestinal complaints, retinal haemorrhages and exudates, and thinning and brittleness of the nails. Among the causes of iron-deficiency anaemia are inadequate iron intake, impaired iron absorption, increased blood loss and increased requirements such as infancy, pregnancy, and lactation. (12 Dec 1998) |
| anaemia, macrocytic | Anaemia characterised by larger than normal erythrocytes, increased mean corpuscular volume (mcv) and increased mean corpuscular haemoglobin (mch). (12 Dec 1998) |
| anaemia, mediterranean | Better known today as thalassaemia (or as beta thalassaemia or thalassaemia major).The clinical picture of this important type of anaemia was first described in 1925 by the paediatrician Thomas Benton Cooley. The name thalassaemia was coined by the Nobel Prise winning pathologist George Whipple and the professor of paediatrics Wm Bradford at U. Of Rochester because thalassa in Greek means the sea (like the Mediterrranean Sea) + -aemia means in the blood so thalassaemia means sea in the blood. Thalassaemia is not just one disease. It is a complex contingent of genetic (inherited) disorders all of which involve underproduction of haemoglobin, the indispensable molecule in red blood cells that carries oxygen. The globin part of normal adult haemoglobin is made up of 2 alpha and 2 beta polypeptide chains. In beta thalassaemia, there is a mutation (change) in both beta globin chains leading to underproduction (or absence) of beta chains, underproduction of haemoglobin, and profound anaemia. The gene for beta thalassaemia is relatively frequent in people of Mediterranean origin (for example, from Italy and Greece). Children with this disease inherit one gene for it from each parent. The parents are carriers (heterozygotes) with just one thalassaemia gene, are said to have thalassaemia minor, and are essentially normal. Their children affected with beta thalassaemia seem entirely normal at birth because at birth we still have predominantly foetal haemoglobin which does not contain beta chains. The anaemia surfaces in the first few months after birth and becomes progressively more severe leading to pallor and easy fatiguability, failure to thrive (grow), bouts of fever (due to infections) and diarrhoea. Treatment based on blood transfusions is helpful but not curative. Gene therapy will, it is hoped, be applicable to this disease. (12 Dec 1998) |
| anaemia, megaloblastic | Anaemia characterised by the presence of megaloblasts in the bone marrow. (12 Dec 1998) |
| anaemia, myelophthisic | Anaemia characterised by appearance of immature myeloid and nucleated erythrocytes in the peripheral blood, resulting from infiltration of the bone marrow by foreign or abnormal tissue. (12 Dec 1998) |