| cyclic AMP-dependent protein kinase | Enzymes which attach phosphate groups to the serine or tyrosine amino acids on proteins as a means of regulating the proteins' activity in metabolic reactions. (09 Oct 1997) |
|---|---|
| cyclic AMP-dependent protein kinases | <enzyme> A group of enzymes that are dependent on cyclic AMP and catalyze the phosphorylation of serine or threonine residues on proteins. Registry number: EC 2.7.10.- (12 Dec 1998) |
| cyclic AMP receptor protein | A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (cyclic AMP receptors), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of cyclic AMP-dependent protein kinases. (12 Dec 1998) |
| cyclic GMP-dependent protein kinases | <enzyme> A group of enzymes that are dependent on cyclic GMP and catalyses the phosphorylation of serine or threonine residues of proteins. Registry number: EC 2.7.10.- (12 Dec 1998) |
| DNA-binding protein, cyclic AMP-responsive | A protein that has been shown to function as a calcium regulated transcription factor as well as a substrate for depolarisation-activated calcium calmodulin-dependent protein kinases I and II. This protein functions to integrate both calcium and camp signals. (12 Dec 1998) |
| adenine nucleotide | A condensation product of adenosine and phosphoric acid; a nucleotide found among the hydrolysis products of all nucleic acids. 3'-Adenylic acid (adenosine 3'-monophosphate) and 5'-adenylic acid (adenosine 5'-monophosphate) differ in the place of attachment of the phosphoric acid to the d-ribose; deoxyadenylic acid differs in having H instead of OH at the 2' position of d-ribose. See: AMP. Synonym: adenine nucleotide. (05 Mar 2000) |
| adenine nucleotide translocase | <enzyme> Catalyses the exchange between endogenous and exogenous adenine nucleotides in mitochondria.ec 2.7.7.-. Registry number: EC 2.7.7.- (12 Dec 1998) |
| xanthine nucleotide | The monophosphoric ester of xanthosine. An intermediate in GMP biosynthesis. Synonym: xanthidylic acid, xanthine nucleotide, xanthylic acid. (05 Mar 2000) |
| pyrimidine-5'-nucleotide nucleosidase | <enzyme> Also acts on some deoxyribonucleotides Registry number: EC 3.2.2.10 Synonym: pyr-5'-nt-nucleosidase (26 Jun 1999) |
| nicotinamide-nucleotide adenylyltransferase | <enzyme> An enzyme that catalyses reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of nmn to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyses the final reaction in the major pathway for the biosynthesis of NAD in mammals. Chemical name: ATP:nicotinamide-nucleotide adenylyltransferase Registry number: EC 2.7.7.1 (12 Dec 1998) |
| nucleotide | <biochemistry> Phosphate esters of nucleosides. The metabolic precursors of nucleic acids are monoesters with phosphate on carbon 5 of the pentose (known as 5' to distinguish sugar from base numbering). However many other structures, such as adenosine 3'5' cyclic monophosphate (cAMP) and molecules with 2 or 3 phosphates are also called nucleotides. (18 Nov 1997) |
| nucleotide binding fold | Protein motif consisting of a fold or pocket with certain conserved residues, required for the binding of nucleotides. (18 Nov 1997) |
| nucleotide deaminases | <enzyme> Catalyze the hydrolysis of nucleotides with the elimination of ammonia. Registry number: EC 3.5.4 (12 Dec 1998) |
| nucleotide deletion | Deletion of a single nucleotide, which in a transcribed gene will lead to a frameshift mutation. Synonym: point deletion. (05 Mar 2000) |
| nucleotide mapping | Two-dimensional separation and analysis of nucleotides. (12 Dec 1998) |