| aspartate 1-decarboxylase | <enzyme> A pyridoxal-phosphate protein that catalyses the alpha-decarboxylation of l-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. The enzyme is found in bacteria and in invertebrate and vertebrate nervous systems. It is the rate-limiting enzyme in determining gaba levels in normal nervous tissues. The brain enzyme also acts on l-cysteate, l-cysteine sulfinate, and l-aspartate. Chemical name: L-Glutamate-1-carboxy-lyase Registry number: EC 4.1.1.15 (12 Dec 1998) |
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| aspartate 4-decarboxylase | Aspartate beta-decarboxylase;a carboxy-lyase converting l-aspartate to l-alanine (releasing CO2); it decarboxylates aminomalonate and (in bacteria) removes SO2 from cysteinesulfinate. See: desulfinase. (05 Mar 2000) |
| aspartate aminotransferase | <enzyme> An enzyme catalyzing the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; a diagnostic aid in viral hepatitis and in myocardial infarctions. Synonym: aspartate transaminase, glutamic-aspartic transaminase, glutamic-oxaloacetic transaminase, serum glutamic-oxaloacetic transaminase. (05 Mar 2000) |
| aspartate ammonia-lyase | <enzyme> An enzyme that catalyses the conversion of aspartic acid to ammonia and fumaric acid in plants and some microorganisms. Chemical name: L-Aspartate ammonia-lyase Registry number: EC 4.3.1.1 (12 Dec 1998) |
| aspartate carbamoyltransferase | <enzyme> An enzyme that catalyses the conversion of carbamoyl phosphate and l-aspartate to yield orthophosphate and n-carbamoyl-l-aspartate. Chemical name: Carbamoyl-phosphate:L-aspartate carbamoyltransferase Registry number: EC 2.1.3.2 (12 Dec 1998) |
| aspartate kinase | <enzyme> An enzyme that catalyses the formation of beta-aspartyl phosphate from aspartic acid and ATP. Threonine serves as an allosteric regulator of this enzyme to control the biosynthetic pathway from aspartic acid to threonine. Chemical name: ATP:L-aspartate 4-phosphotransferase Registry number: EC 2.7.2.4 (12 Dec 1998) |
| aspartate N-acetyltransferase | <enzyme> Nervous system enzyme that mediates synthesis of n-acetylaspartic acid; utilises acetyl-CoA Registry number: EC 2.3.1.17 (26 Jun 1999) |
| aspartate transaminase | <enzyme> An enzyme of the transferase class that catalyses the reaction of l-aspartate and 2-ketoglutarate to yield oxaloacetate and l-glutamate. The enzyme is a pyridoxal phosphate protein. In the liver the reaction transfers excess metabolic nitrogen into aspartate for disposal in the urea cycle. Chemical name: L-Aspartate:2-oxoglutarate aminotransaminase Registry number: EC 2.6.1.1 (12 Dec 1998) |
| aspartate-alpha-decarboxylase | <enzyme> Forms beta-alanine Registry number: EC 4.1.1.11 Synonym: aspartate 1-decarboxylase (26 Jun 1999) |
| aspartate-ammonia ligase | <enzyme> An enzyme that catalyses the formation of asparagine from ammonia and aspartic acid, in the presence of ATP. Chemical name: L-Aspartate:ammonia ligase (AMP-forming) Registry number: EC 6.3.1.1 (12 Dec 1998) |
| aspartate-saemialdehyde dehydrogenase | <enzyme> An enzyme that catalyses the conversion of l-aspartate 4-saemialdehyde, orthophosphate, and NADP+ to yield l-4-aspartyl phosphate and NADPH. Chemical name: L-Aspartate-4-saemialdehyde:NADP+ oxidoreductase (phosphorylating) Registry number: EC 1.2.1.11 (12 Dec 1998) |
| aspartate-trna ligase | <enzyme> An enzyme that activates aspartic acid with its specific transfer RNA. Chemical name: L-Aspartate:tRNA-(Asp) ligase (AMP-forming) Registry number: EC 6.1.1.12 (12 Dec 1998) |
| aspartic | <chemistry> Pertaining to, or derived, asparagine; as, aspartic acid. Source: Websters Dictionary (01 Mar 1998) |
| aspartic acid | <amino acid> One of the twenty naturally occurring amino acids. Has the following chemical characteristics: pKa1 pKa2 pKa3 pI Water Solubility (30deg C)2.09-3.86 9.82 2.97 0.6 (09 Oct 1997) |
| aspartic acid 2-oxoglutarate-dependent dioxygenase | <enzyme> Hydroxylates one aspartic acid residue in the first egf-like unit of factor ix Registry number: EC 1.14.11.- Synonym: aspartate 2-oxoglutarate dioxygenase, asp-2-og-dioxygenase, aspartyl beta-hydroxylase, aspartyl (asparaginyl) beta-hydroxylase (26 Jun 1999) |