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5,5-diphenylhydantoin <drug> A medication commonly used to treat seizure disorders and epilepsy.
(15 Oct 1997)
5,6,7,8-tetrahydrofolate dehydrogenase <enzyme> An enzyme involved in the biosynthesis of folic acid coenzymes, that transfers hydrogen from NADP to dihydrofolate, yielding tetrahydrofolic acid. Inhibitors can be used as antimicrobial and anticancer drugs. Standard source is liver and the enzyme is used to assay dihydrofolate.
(18 Nov 1997)
5,6-dihydroxytryptamine <chemical> Tryptamine substituted with two hydroxyl groups in positions 5 and 6. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacologic research.
Pharmacological action: serotonin agents.
Chemical name: 1H-Indole-5,6-diol, 3-(2-aminoethyl)-
(12 Dec 1998)
5,6-dimethylbenzimidazole A structural moiety found in one of the cobalamins.
(05 Mar 2000)
5,7-dihydroxytryptamine <chemical> Tryptamine substituted with two hydroxyl groups in positions 5 and 7. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacology as a tool.
Pharmacological action: serotonin agents.
Chemical name: 1H-Indole-5,7-diol, 3-(2-aminoethyl)-
(12 Dec 1998)
5,8,11,14,17-eicosapentaenoic acid <chemical> Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
Chemical name: 5,8,11,14,17-Eicosapentaenoic acid
(12 Dec 1998)
5,8,11,14-eicosatetraynoic acid <chemical> A 20-carbon unsaturated fatty acid containing 4 alkyne bonds. It inhibits the enzymatic conversion of arachidonic acid to prostaglandins e(2) and f(2a).
Chemical name: 5,8,11,14-Eicosatetraynoic acid
(12 Dec 1998)
5-aminoimidazole ribose 5'-phosphate 5-amino-1-beta-d-ribofuranosylimidazole 5'-phosphate;an intermediate in the biosynthesis of purines.
Synonym: 5-aminoimidazole ribotide.
Acronym: AIR
(05 Mar 2000)
5-aminoimidazole ribotide 5-amino-1-beta-d-ribofuranosylimidazole 5'-phosphate;an intermediate in the biosynthesis of purines.
Synonym: 5-aminoimidazole ribotide.
Acronym: AIR
(05 Mar 2000)
5-aminoimidazole-4-N-succinocarboxamide ribonucleotide An intermediate in purine biosynthesis.
(05 Mar 2000)
5-aminolevulinate synthetase <enzyme> An enzyme of the transferase class that catalyses condensation of the succinyl group from succinyl coenzyme a with glycine to form delta-aminolevulinate. It is a pyridoxyl phosphate protein and the reaction occurs in mitochondria as the first step of the haem biosynthetic pathway. The enzyme is a key regulatory enzyme in haem biosynthesis and, in liver at least, is feedback inhibited by haem.
Chemical name: Succinyl-CoA:glycine C-Succinyltransferase (decarboxylating)
Registry number: EC 2.3.1.37
(12 Dec 1998)
5-aminosalicylic acid 1,2-dioxygenase <enzyme> Converts 5-aminosalicylic acid to 4-amino-6-carboxy-2-oxohexa-3,5-dienoate
Registry number: EC 1.13.11.-
Synonym: asa-1,2-dioxygenase
(26 Jun 1999)
5-aminovalerate aminotransferase <enzyme> Transfers amino group from delta-aminovaleric acid to alpha-ketoglutarate
Registry number: EC 2.6.1.48
Synonym: delta-aminovalerate-alpha-ketoglutarate aminotransferase
(26 Jun 1999)
5-bromouracil Synthetic analogue (antimetabolite) of thymine, in which a bromine atom takes the place of the methyl group in thymine; a mutagen.
(05 Mar 2000)
5-bromouracil reductase <enzyme> Requires NADPH, proposed to reduce 5-bromouracil to 5-bromohydroxyuracil
Registry number: EC 1.1.1.-
(26 Jun 1999)
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