| 1-MeAde | 1-Methyladenine |
|---|---|
| 1-Methyl-2-Pyrrolidinyl | S)-3-Methyl-5 |
| 1-MU | 1-methyl uric acid |
| 1-MX | 1-methyl xanthine |
| 1-NOP | 1-nitrosopyrene |
| 1-NP | 1(1-naphthyl) piperazine |
| 1-NP | 1-Nitropyrene |
| 1-OHP | of 1-hydroxypyrene |
| 1-PP | 1-(2--pyrimidinyl)piperazine |
| 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | <chemical> 1,2,3,6-tetrahydro-1-methyl-4-phenylpyridine. A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in parkinson disease. These toxic effects can be prevented by the administration of selective monoamine oxidase inhibitors. Since the cellular toxicity of the compound is similar to that observed in idiopathic parkinson disease, experimental studies with this compound can suggest new opportunities for effective therapy. The compound also induces duodenal ulcers. Pharmacological action: dopamine agents. Chemical name: Pyridine, 1,2,3,6-tetrahydro-1-methyl-4-phenyl- (12 Dec 1998) |
|---|---|
| 1-methyl-4-phenylpyridinium | <chemical> 1-methyl-4-phenylpyridinium (mpp+). An active neurotoxic metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp). The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to paraquat, has also been used as an herbicide. Pharmacological action: dopamine agents, herbicides. Chemical name: Pyridinium, 1-methyl-4-phenyl- (12 Dec 1998) |
| 1-naphthylamine | <chemical> 1-naphthalenamine. A suspected industrial carcinogen (and listed as such by osha). Its n-hydroxy metabolite is strongly carcinogenic and mutagenic. Pharmacological action: carcinogens. Chemical name: 1-Naphthalenamine (12 Dec 1998) |
| 1-naphthylisothiocyanate | <chemical> 1-isothiocyanatonaphthalene. A tool for the study of liver damage which causes bile stasis and hyperbilirubinaemia acutely and bile duct hyperplasia and biliary cirrhosis chronically, with changes in hepatocyte function. It may cause skin and kidney damage. Chemical name: Naphthalene, 1-isothiocyanato- (12 Dec 1998) |
| 1-nitropyrene reductase | <enzyme> Nadh or NADPH can serve as reducing agent to form 1-aminopyrene Registry number: EC 1.7.- Synonym: 1-nitropyrene nitroreductase (26 Jun 1999) |
| 1-O-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine desaturase | <enzyme> Alkylacylglycerophosphorylethanolamine alk-1-enylacyl-glycerophosphorylethanolamine (ethanolamine plasmalogen) type of reaction (cis-olefination), cofactor requirement resembles fatty acid desaturases Registry number: EC 1.14.99.- (26 Jun 1999) |
| 1-octanol | <chemical> A colourless, slightly viscous liquid used as a defoaming or wetting agent. It is also used as a solvent for protective coatings, waxes, and oils, and as a raw material for plasticisers. Pharmacological action: solvents. (12 Dec 1998) |
| 1-phosphatidylinositol 3-kinase | <enzyme> An enzyme that catalyses the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, v(d)j recombination and cell cyle checkpoints.37. Chemical name: ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase Registry number: EC 2.7.1.137 (12 Dec 1998) |
| 1-phosphatidylinositol 4-kinase | <enzyme> An enzyme that catalyses the conversion of phosphatidylinositol to phosphatidylinositol 4-phosphate, the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Chemical name: ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate Registry number: EC 2.7.1.67 (12 Dec 1998) |
| 1-phosphofructaldolase | <enzyme> An enzyme of the lyase class that catalyses the cleavage of fructose 1,6-biphosphate to form dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. The enzyme also acts on (3s,4r)-ketose 1-phosphates. The yeast and bacterial enzymes are zinc proteins. (enzyme nomenclature, 1992) e.c. 4.1.2.13. Chemical name: D-Fructose-1,6-biphosphate D-glyceraldehyde-3-phosphate-lyase Registry number: EC 4.1.2.13 (12 Dec 1998) |
| 1-phosphofructokinase | <enzyme> From rhodobacter capsulatus fruk gene; catalyses d-fructose 1-phosphate to yield d-fructose 1,6-bisphosphate in presence of ATP; itp, GTP and utp can replace ATP Registry number: EC 2.7.1.56 Synonym: fructose 1-phosphate kinase, fruk gene product, phosphofructo-1-kinase (26 Jun 1999) |
| 1-propanol | <chemical> A colourless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate. Chemical name: 1-Propanol (12 Dec 1998) |
| 1-pyrroline-5-carboxylate dehydrogenase | <enzyme> Catalyses the oxidation of 1-pyrroline-5-carboxylate to l-glutamate in the presence of nad; see also record for glutamate-saemialdehyde dehydrogenase which converts 5-glutamyl phosphate to glutamate 5-saemialdehyde and phosphate in the presence of NADPH Registry number: EC 1.5.1.12 Synonym: delta(1)-pyrroline-5-carboxylate dehydrogenase, glutamic-gamma-saemialdehyde dehydrogenase, nadp+ specific 8-glutamate saemialdehyde dehydrogenase, ggs dehydrogenase, delta-1-pyrroline-5-carboxylate synthetase, p5cs enzyme, glutamyl-gamma-saemialdehyde dehydrogenase (26 Jun 1999) |
| 1-ribosylorotate | Orotic acid-3-beta-d-ribonucleoside; uridine-6-carboxylic acid;elevated in cases of orotidinuria. Synonym: 1-ribosylorotate. Abbreviation: Ord (05 Mar 2000) |
| 1-sarcosine-8-isoleucine angiotensin II | <chemical> An angiotensin II analog which acts as a highly specific inhibitor of angiotensin II. Pharmacological action: angiotensin-converting enzyme inhibitors, antihypertensive agents. Chemical name: Angiotensin II, 1-(N-methylglycine)-8-L-isoleucine- (12 Dec 1998) |
Synonyms : 3-Amino-1, 1, 3-propanetricarboxylic Acid, 1 Carboxyglutamic Acid, gamma Carboxyglutamate, gamma Carboxyglutamic Acid
Synonyms : 1, 5-Dideoxy-1, 5-imino-D-mannitol, 1-Deoxynojirimycin Hydrochloride, Bay n 5595, Moranoline, 1 Deoxymannojirimycin, 1 Deoxynojirimycin, 1 Deoxynojirimycin Hydrochloride
Synonyms : IBMX, 1 Methyl 3 isobutylxanthine, 3 Isobutyl 1 methylxanthine
Synonyms : N-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine
Synonyms : 1-Methyl-4-phenylpyridine, 1-Methyl-4-phenylpyridinium Chloride, 1-Methyl-4-phenylpyridinium Ion, N-Methyl-4-phenylpyridine, N-Methyl-4-phenylpyridinium, 1 Methyl 4 phenylpyridine, 1 Methyl 4 phenylpyridinium, 1 Methyl 4 phenylpyridinium Chloride