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oncocytosis metaplasia of oncocytes.
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oncofetal occurring both in tumor tissue and during fetal development; see under antigen.
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oncofetal a. an antigenic gene product that is expressed during fetal development, partially or completely repressed in adult tissues, and derepressed in some tissues that have undergone neoplastic transformation; oncofetal antigens, e.g., alpha-fetoprotein, carcinoembryonic antigen, and pancreatic oncofetal antigen, are thus useful tumor markers.
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oncogenetic pertaining to or characterized by oncogenesis.
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oncogenic o. a type seen in association with usually benign mesenchymal neoplasms. The tumors appear to produce a substance that impairs renal tubular functions such as phosphate transport and hydroxylation of 25-hydroxyvitamin D; hypophosphatemia secondary to reduced renal resorption of phosphate is a major cause of the bone disease. Called also tumor-induced o.
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