| properdin factor b | <enzyme> A glycine-rich, heat-labile beta-glycoprotein found in blood. It is a proactivator of complement 3 in the alternate pathway of complement activation. Factor b is converted by factor d to c3 convertase. Registry number: EC 3.4.21.47 (12 Dec 1998) |
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| properdin factor d | <enzyme> A serum protein which during the alternate pathway of complement activation converts the inactive properdin factor b to c3 convertase. Registry number: EC 3.4.21.46 (12 Dec 1998) |
| properdin factor E | A serum protein (mw 160,000) required for activation of C3 (third component of complement) by cobra venom factor. See: properdin system. (05 Mar 2000) |
| scatter factor | A motility factor (motogen) isolated from conditioned medium in which human fibroblasts have been grown. It causes colonies of epithelial and endothelial cells, in culture, to separate into single cells that move apart i.e. They scatter. It has been shown to be identical to human hepatocyte growth factor, but it is not mitogenic for all cell types. (18 Nov 1997) |
| proteinase inhibitor inducing factor | See: PIIF. (18 Nov 1997) |
| protein factor | The factor (6.25) by which the nitrogen content of a protein is multiplied to give the amount of protein. (05 Mar 2000) |
| HG factor | A polypeptide hormone (3485 D) secreted by the cells of the Islets of Langerhans in response to a fall in blood sugar levels. Induces hyperglycaemia. A family of structurally related peptides includes glucagon like peptides 1 & 2 (encoded by the same gene), gastric inhibitory polypeptide, secretin, vasoactive intestinal peptide, growth hormone releasing factor, pituitary adenylate cyclase activating polypeptide, exendins. (18 Nov 1997) |
| x factor | <biochemistry> A precursor necessary to synthesise cytochromes. (09 Oct 1997) |
| psi factor | A protein responsible for the specific initiation of the RNA polymerase-catalyzed reaction at the promoter sites of genes. (05 Mar 2000) |
| secretor factor | <haematology> The capacity to secrete antigens of the ABO blood group in saliva and other body fluids, controlled by a pair of allelic genes designated Se and se (or S and s), with the Se phenotype dominant to se. The saliva of genotypes SeSe and Sese contains the blood group substances A, B, or H found in their erythrocytes; the saliva of nonsecretors (genotype sese) contains no blood group substance; tests for ABH secretion are useful in genetic linkage and population studies; the secretor phenomenon is also closely associated with the Lewis blood group. (05 Mar 2000) |
| human antihemophilic factor | A lyophilised concentrate of factor VIII, obtained from fresh normal human plasma; used as a haemostatic agent in haemophilia. Synonym: antihemophilic globulin, human antihemophilic fraction. (05 Mar 2000) |
| serum factor VIII antigen | A test used to measure the activity of a blood clotting factor VIII (Von Willebrand factor). This test is usually used to monitor treatment of haemophilia. Abnormally low factor VIII assays may be seen in the following conditions: congenital deficiency of factor VIII (haemophilia), DIC and secondary fibrinolysis. This test may also be performed in the evaluation of Von Willebrand's disease. (27 Sep 1997) |
| serum response factor | Transcription factor that binds to the serum response element upstream of the site of transcription initiation of genes such as c fos. (18 Nov 1997) |
| pyruvate oxidation factor | <biochemistry> 1,2 dithiolane 3 valeric acid. Regarded as a coenzyme in the oxoglutarate dehydrogenase complex of the citric acid cycle. Involved generally in oxidative decarboxylations of _ keto acids. A growth factor for some organisms. (18 Nov 1997) |
| sex factor | The prototype conjugative plasmid associated with conjugation in the K-12 strain of Escherichia coli. Synonym: F agent, F-factor, F genote, F-genote, fertility agent, fertility factor, sex factor. (05 Mar 2000) |