| DRF | Daily Rating Form; daily replacement factor; Deafness Research Foundation; dose reduction factor |
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| EDF | eosinophil differentiation factor; erythroid differentiation factor; extradural fluid |
| EIF | erythrocyte initiation factor; eukaryotic initiation factor |
| FF | degree of fineness of abrasive particles; fat-free; father factor; fecal frequency; fertility factor... |
| GF | gastric fistula; gastric fluid; germ-free; glass factor; glomerular filtration; gluten-free; grandfa... |
| suppressor factor | <immunology> Factors released by T suppressor cells. See: suppressor mutation, ochre suppressor, opal suppressor. (19 Jan 1998) |
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| diabetogenic factor | Rarely used term for a factor in crude extracts of the anterior lobe of the hypophysis that produces degenerative changes in the islet cells of the pancreas and causes permanent diabetes. (05 Mar 2000) |
| diffusing factor | <enzyme> Enzyme that degrades hyaluronic acid, found in lysosomes. (18 Nov 1997) |
| direct lytic factor of cobra venom | A polypeptide of 62 residues; action on cells is similar to that of melittin in that it promotes disruption of membranes; used as an investigational antirheumatic agent. Synonym: cobra toxin, direct lytic factor of cobra venom. (05 Mar 2000) |
| Duran-Reynals permeability factor | <enzyme> Enzyme that degrades hyaluronic acid, found in lysosomes. (18 Nov 1997) |
| duty factor | <radiobiology> Ratio of the duration of time when a system is actually operating to the total time for a complete cycle of the system. For example: if a tokamak experiment runs for 5 seconds and then sits for 500 seconds while the power supplies are recharged, then the duty factor is 1%. Similar to capacity factor for powerplants. Synonym: duty cycle. (09 Oct 1997) |
| q-factor | <radiobiology> Ratio of power produced by fusion to power put into the reactor to heat the plasma and drive the magnetic fields. Q = 1 is the definition of scientific breakeven, where power out = power in. Economical fusion will require Q significantly greater than 1. Fortunately Q increases dramatically as the plasma parameters approach the Lawson criterion for ignition. Power to drive the magnetic fields is frequently ignored in discussions of Q, with the justification that a steady-state, continuous-output fusion reactor will have superconducting magnet coils. (15 Dec 1997) |
| quality factor | <radiobiology> (Q) A multiplying factor used with absorbed dose to convert to dose equivalent and therefore to express the radiation's effectiveness in causing biological effects. (16 Dec 1997) |
| inhibition factor | <growth factor> A soluble, nondialysable factor that is produced by sensitised lymphocytes following exposure to a specific antigen. It inhibits macrophage migration and causes adherence. It was originally defined on the basis of inhibition of emigration of mononuclear cells from capillary (haematocrit) tubes, more recently a 13 kD protein with migration inhibitory activity has been isolated. Acronym: MIF Synonym: inhibition factor. (22 Sep 2002) |
| initiation factor | One of several soluble proteins involved in the initiation of protein or RNA synthesis. (05 Mar 2000) |
| integrin modulating factor 1 | <chemical> A lipid that alters the function of leukocyte integrins; may be an unsaturated fatty acid or an isoprenoid acid Synonym: imf 1, imf-1 (05 Dec 1998) |
| intrinsic factor | A mucoprotein normally secreted by the epithelium of the stomach and that binds vitamin B12, the intrinsic factor/B12 complex is selectively absorbed by the distal ileum, though only the vitamin is taken into the cell. (18 Nov 1997) |
| T-cell growth factor | <cytokine> A hormone-like substance released by stimulated T lymphocytes, causes activation and differentiation of other T lymphocytes independently of antigen. A type of interleukin, a chemical messenger, a substance that can improve the body's response to disease. It stimulates the growth of certain disease-fighting blood cells in the immune system. It is secreted by Thl CD4 cells to stimulate CD8 cytotoxic T-1yrnphocytes. Interleukin 2 also increases the proliferation and maturation of the CD4 cells themselves. During HIV infection, Interleukin-2 production gradually declines. Use of interleukin 2 therapy is under study as a way to raise CD4 cell counts and restore immune function. Acronym: IL-2 (12 Dec 1998) |
| T-cell growth factor-1 | <cytokine> A hormone-like substance released by stimulated T lymphocytes, causes activation and differentiation of other T lymphocytes independently of antigen. A type of interleukin, a chemical messenger, a substance that can improve the body's response to disease. It stimulates the growth of certain disease-fighting blood cells in the immune system. It is secreted by Thl CD4 cells to stimulate CD8 cytotoxic T-1yrnphocytes. Interleukin 2 also increases the proliferation and maturation of the CD4 cells themselves. During HIV infection, Interleukin-2 production gradually declines. Use of interleukin 2 therapy is under study as a way to raise CD4 cell counts and restore immune function. Acronym: IL-2 (12 Dec 1998) |
| T-cell growth factor-2 | <cytokine> A soluble cytokine factor produced by activated T-lymphocytes that promotes antibody production by causing proliferation and differentiation of B-cells. Interleukin-4 induces the expression of class II major histocompatibility complex and fc receptors on B-cells. It also acts on T-lymphocytes, mast cell lines, and several other haematopoietic lineage cells including granulocyte, megakaryocyte, and erythroid precursors, as well as macrophages. Acronym: IL-4 (12 Dec 1998) |
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