| human genome project | <molecular biology> A worldwide project to determine the DNA sequence of all the DNA in humans, funded primarily by the U.S. Department of Energy (DOE), the U.S. National Institutes of Health (NIH), the European Commission (EC), and the pharmaceutical and biotechnology industries. The project will be completed in stages, beginning with a genetic map of man and a sequencing of all human cDNA. As part of the Human Genome Project, the genomes of several other plant and animal models are being studied. (14 Nov 1997) |
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| human granulocytic ehrlichiosis | A form of ehrlichiosis in a patient with a history of tick bite. Characterised by leukopenia, thrombocytopenia, and mild liver damage. (Thought to be predominantly a granulocytic form of ehrlichiosis.) The species of Ehrlichia that is the agent of this disease is unknown at present. (05 Mar 2000) |
| human growth hormone | <endocrinology> A protein produced in the pituitary gland that stimulates the liver to produce somatomedins, which stimulate growth of bone and muscle. (09 Oct 1997) |
| human herpesvirus 1 | Herpes simplex virus, type 1. See: herpes simplex. (05 Mar 2000) |
| human herpesvirus 2 | Herpes simplex virus, type 2. See: herpes simplex. (05 Mar 2000) |
| human herpesvirus 3 | A herpesvirus, morphologically identical to herpes simplex virus, that causes varicella (chickenpox) and herpes zoster in man; varicella results from a primary infection with the virus; herpes zoster results from secondary invasion by the same virus or by reactivation of infection which in many instances has been latent for many years. Synonym: chickenpox virus, herpes zoster virus, human herpesvirus 3. (05 Mar 2000) |
| human herpesvirus 4 | <virology> Species of Herpetoviridae that is responsible for infectious mononucleosis (glandular fever). Discovered in 1964, this virus has been associated with Burkitt's lymphoma in South African children and with nasopharyngeal carcinoma in Asian populations. (27 Sep 1997) |
| human herpesvirus 5 | <virology> Probably the most widespread of the Herpetoviridae group. Infected cells enlarge and have a characteristic inclusion body (composed of virus particles) in the nucleus. Causes disease only in utero (leading to abortion or stillbirth or to various congenital defects), although can be opportunistic in the immunocompromised host. Patients who have been exposed to the virus will remain cytomegalovirus IgG positive. Acronym: CMV (30 Sep 1997) |
| human herpesvirus 6 | A recently discovered human herpesvirus that was found in certain lymphoproliferative disorders, replicates in a number of different types of leukocytes, and is associated with the childhood disease roseola (exanthema subitum). (05 Mar 2000) |
| human herpesvirus 7 | This virus has recently been discovered in association with human lymphocytes; however, a causal relationship to any known disease has not been determined. (05 Mar 2000) |
| human immunodeficiency virus | <virology> A type of retrovirus (human immunodeficiency virus) that is responsible for the fatal illness acquired immunodeficiency syndrome. Two strains have been identified. Type 1: the retrovirus recognised as the agent that induces AIDS. Type 2: a virus closely related to HIV-1 that also leads to immune suppression. HIV-2 is not as virulent as HIV-1 and is epidemic only in West Africa. Acronym: HIV (11 Nov 1997) |
| human leukaemia-associated antigens | Antigen's on the surface of leukaemic cells which seem not to be present on the surfaces of the same type of normal cells; the myeloblast antigen of acute myelogenous leukaemia found in chronic myelogenous leukaemia is thought to be associated with a "blastic" transformation. (05 Mar 2000) |
| human measles immune serum | Obtained from the blood of a healthy person who has survived an attack of measles. Synonym: measles convalescent serum. (05 Mar 2000) |
| human menopausal gonadotropin | A hormone of pituitary originally obtained from the urine of postmenopausal women now produced synthetically; used to induce ovulation. See: menotropins. (05 Mar 2000) |
| human normal immunoglobulin | A preparation of the proteins of liquid human plasma, containing the antibodies of normal adults; it is obtained from pooled liquid human plasma from a number of donors and may be prepared by precipitation with organic solvents under controlled conditions of pH, ionic strength, and temperature. Synonym: human normal immunoglobulin. (05 Mar 2000) |