| Rothera's nitroprusside test | A test for ketone bodies; 5 ml of fresh urine are saturated with solid ammonium sulfate and mixed with 10 drops of freshly prepared 2% sodium nitroprusside solution, which is then mixed with 10 drops of concentrated ammonia water and allowed to stand for 15 min; the presence of acetoacetic acid, or of larger concentrations of acetone, is indicated by the development of a blue-purple colour. (05 Mar 2000) |
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| phenolsulfonphthalein test | An obsolete test for renal function; after the patient has drunk a glass or two of water, 1 ml of a 0.6% solution of dye is injected hypodermically; the time between this injection and the appearance of a pink tinge in the urine as it falls into an alkaline solution is noted; the amount excreted in each of the next 2 hours is then estimated colourimetrically. Synonym: Geraghty's test, phthalein test, red test, Rowntree and Geraghty test. (05 Mar 2000) |
| phentolamine test | A test for pheochromocytoma; intravenous administration of phentolamine (5 mg) reduces hypertension due to a pheochromocytoma but not that due to other causes, e.g., essential hypertension; the blood pressure is raised by the drug in the latter form of hypertension. (05 Mar 2000) |
| microhemagglutination-Treponema pallidum test | A microtiter version of the Treponema pallidum haemagglutination test. Synonym: MHA-TP test. (05 Mar 2000) |
| Rowntree and Geraghty test | An obsolete test for renal function; after the patient has drunk a glass or two of water, 1 ml of a 0.6% solution of dye is injected hypodermically; the time between this injection and the appearance of a pink tinge in the urine as it falls into an alkaline solution is noted; the amount excreted in each of the next 2 hours is then estimated colourimetrically. Synonym: Geraghty's test, phthalein test, red test, Rowntree and Geraghty test. (05 Mar 2000) |
| RPR test | A group of serologic test's for syphilis in which unheated serum or plasma is reacted with a standard test antigen containing charcoal particles; positive test's yield a flocculation. A modification, called the RPR (circle) card test, is widely used as a screening test. Synonym: RPR test. (05 Mar 2000) |
| RSV test | <investigation> A blood test which measures the levels of immunoglobulins IgG and IgM against respiratory syncytial virus (RSV). (17 Dec 1997) |
| rubella HI test | A haemagglutination inhibition (HI) test for rubella, often performed routinely as part of a prenatal workup of the pregnant woman; the presence of any detectable HI titre in the absence of disease indicates previous infection and immunity to reinfection; if HI antibody is undetected, the patient is considered potentially susceptible and is followed accordingly. See: haemagglutination inhibition. (05 Mar 2000) |
| microprecipitation test | A precipitation test in which reduced quantities of test reagents are used. (05 Mar 2000) |
| Rubin test | An obsolete test of patency of the fallopian tubes; a cannula is introduced into the cervix uteri, and carbon dioxide gas is passed through the cannula by means of a syringe with manometer attachment; if the tubes are patent, the escape of gas into the abdominal cavity is evidenced by a high-pitched bubbling sound heard on auscultation over the lower abdomen, or free gas under the diaphragm can be demonstrated by X-ray. (05 Mar 2000) |
| Rubner's test | A test for lactose or glucose in the urine; lead acetate is added to the suspected urine which is then filtered; ammonia is added until a permanent precipitate is formed; if lactose is present, the precipitate will take on a pink to red colour when the fluid is heated; if there is glucose, the colour will be yellow to brown. (05 Mar 2000) |
| Rumpel-Leede test | A tourniquet test for capillary fragility, often positive in the presence of severe thrombocytopenia. See: capillary fragility test. Synonym: bandage sign, Hess' test, Rumpel-Leede sign. (05 Mar 2000) |
| migration inhibition test | A test which measures the presence of migration-inhibitory factor. Usually peritoneal macrophages are placed in a capillary tube in the presence or absence of supernatants from activated T-cells. If MIF is present, the migration of monocyte/macrophages is reduced. Synonym: macrophage migration inhibition test, migration inhibition test. (05 Mar 2000) |
| migration-inhibitory factor test | A test which measures the presence of migration-inhibitory factor. Usually peritoneal macrophages are placed in a capillary tube in the presence or absence of supernatants from activated T-cells. If MIF is present, the migration of monocyte/macrophages is reduced. Synonym: macrophage migration inhibition test, migration inhibition test. (05 Mar 2000) |
| cis trans test | <molecular biology> The complementation test with two or more interacting genes placed in cis and in trans relationships to each other. A double mutant genome is used in the cis test made from the two single mutant genomes used in the trans test by recombination. If the wild type phenotype is restored by both cis and trans arrangements it is concluded that the two mutations are in different genes and hence that the phenotype is determined by more than one gene. If the trans test is negative and the cis positive this means that the two mutations are in the same gene. If both tests are negative then at least one of the mutations must be dominant. Thus the double test provides a means of fine mapping of genes. A lab test which is used to determine whether two mutations of different genes which affect the same phenotype are on the same functional unit (indicating a cis configuration of the mutated genes) or on different functional units (indicating a trans configuration of the mutated genes). (A functional unit can be a chromosome.) The test is done by mating an individual that has one of the mutations to an individual that has the other one, and observing whether their offspring have the mutant phenotype. If the offspring do not have the mutant phenotype, then the genes are known to be trans, because the offspring have normal copies of each mutant gene on the different functional units which are able to genetically complement each other. If the offspring do have the mutant phenotype, then the genes are known to be cis, because the offspring will always inherit at least one of the mutant genes on the one functional unit, resulting in the mutant phenotype. (09 Oct 1997) |