| CNS | central nervous system; clinical nurse specialist; coagulase-negative staphylococci; congenital neph... |
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| CNS-L | central nervous system leukemia |
| COI | Central Obesity Index; certificate of insurance; cost of illness |
| CP | candle power; capillary pressure; cardiac pacing; cardiac performance; cardiopulmonary; caudate puta... |
| CPC | central posterior curve; cerebellar Purkinje cell; cerebral palsy clinic; cerebral performance categ... |
| Busquet's disease | An osteoperiostitis of the metatarsal bones, leading to exostoses on the dorsum of the foot. (05 Mar 2000) |
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| Buss disease | An acute, septic encephalomyelitis, pleuritis, and peritonitis of cattle caused by Chlamydia psittaci; it occurs in the north central United States. Synonym: Buss disease. (05 Mar 2000) |
| busse-buschke disease | <disease> An acute, subacute or chronic infection by the fungal organism, Cryptococcus neoformans. Infection generally causes a pulmonary infection but may also disseminate to the meninges. The pulmonary form is generally mild and transient (often unrecognised). With dissemination lesions may occur in the skeletal, cutaneus and visceral tissues. The most commonly recognised dissemination is to the central nervous system (meningitis). (27 Sep 1997) |
| Byler disease | Familial intrahepatic cholestasis, with early onset of loose, foul-smelling stools, jaundice, hepatosplenomegaly, and dwarfism, due to an error in conjugated bile salt metabolism; autosomal recessive inheritance. Origin: Byler, an Amish kindred (05 Mar 2000) |
| caffey disease | <radiology> Infantile cortical hyperostosis, aetiology unknown, onset before 5 months of age, hyperostosis and periosteal reaction, mandible (80-95%), clavicles, ribs, long bones (DIAPHYSES often asymmetric) Differential diagnosis: if metaphyses involved, consider battery (child abuse) (12 Dec 1998) |
| Caffey's disease | Neonatal subperiosteal bone formation over many bones, especially the mandible and clavicles and the shafts of long bones; it follows fever, usually appearing before 6 months of age and disappearing during childhood. Synonym: Caffey's disease, Caffey's syndrome, Caffey-Silverman syndrome. (05 Mar 2000) |
| caisson disease | See: decompression sickness Origin: Fr. Caisson (fr. Caisse, a chest) a water-tight box or cylinder containing air under high pressure used in sinking structural pilings underwater (05 Mar 2000) |
| calcium pyrophosphate deposition disease | <radiology> Manifestations can occur singly or in any combination, pseudogout, acute crystal-induced synovitis with clinical symptoms analogous to gout, arthropathy, beaklike osteophytes of 2nd, 3rd metacarpal heads, subchondral cysts (especially carpal bones), unusual distribution of disease (radiocarpal/ulnar joint, patellofemoral joint), SLAC - scapholunate advanced collapse, chondrocalcinosis, triangular fibrocartilage, symphysis pubis, menisci of knee, annulus fibrosus of intervertebral disk (12 Dec 1998) |
| Calve-Perthes disease | perthes disease |
| camurati-engelmann disease | <radiology> Sclerosing diaphyseal dysplasia, does not involve metaphysis, epiphysis, or bone marrow cavity Cf: Albers-Schoenberg disease (12 Dec 1998) |
| canavan disease | Spongy degeneration of cerebral white matter, a rare autosomal recessive form of leukodystrophy. It is characterised by early onset, widespread demyelination and vacuolation of the white matter that gives rise to a spongy appearance, severe mental retardation, megalocephaly, atony of the neck muscles, spasticity of the extremities, and blindness. Death occurs at about 18 months of age. (12 Dec 1998) |
| Canavan's disease | Autosomal recessive degenerative disease of infancy; mostly in Jewish infants; onset typically within first 3-4 months of birth, consisting of blindness, psychomotor regression, enlarged head, optic atrophy, hypotonia, spasticity, increased N-acetylaspartic acid urinary excretion. MRI shows enlarged brain, decreased attenuation of cerebral and cerebellar white matter, and normal ventricles. Pathologically, there is increased brain volume and weight, and spongy degeneration in the subcortical white matter. See: leukodystrophy. Synonym: Canavan's sclerosis, Canavan-van Bogaert-Bertrand disease, spongy degeneration of infancy. (05 Mar 2000) |
| Canavan-van Bogaert-Bertrand disease | Autosomal recessive degenerative disease of infancy; mostly in Jewish infants; onset typically within first 3-4 months of birth, consisting of blindness, psychomotor regression, enlarged head, optic atrophy, hypotonia, spasticity, increased N-acetylaspartic acid urinary excretion. MRI shows enlarged brain, decreased attenuation of cerebral and cerebellar white matter, and normal ventricles. Pathologically, there is increased brain volume and weight, and spongy degeneration in the subcortical white matter. See: leukodystrophy. Synonym: Canavan's sclerosis, Canavan-van Bogaert-Bertrand disease, spongy degeneration of infancy. (05 Mar 2000) |
| cancer, hodgkin's disease | A type of lymphoma (cancer of the lymphatic system). The most common symptom of Hodgkin's disease is a painless swelling in the lymph nodes in the neck, underarm, or groin. Hodgkin's disease is diagnosed when abnormal tissue is detected by a pathologist after a biopsy of an enlarged lymph node. Treatment usually includes radiation therapy or chemotherapy. Regular follow-up examinations are important after treatment for Hodgkin's disease. Patients treated for Hodgkin's disease have an increased risk of developing other types of cancer later in life, especially leukaemia. (12 Dec 1998) |
| canine parvovirus disease | An acute disease of dogs with a variable mortality rate caused by the canine parvovirus; seen in three distinct clinical forms; a generalised neonatal disease, a severe nonsuppurative myocarditis, and a frequently fatal enteritis. (05 Mar 2000) |