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MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 19
  • Steroid 11-beta-Hydroxylase - »õâ A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
    Synonyms : 11 beta-Hydroxylase, CYP 11B1, Cytochrome P450 11B1, Steroid 11 Hydroxylase, Steroid 11-Hydroxylase, Steroid-11-Hydroxylase, 11 beta Hydroxylase, Cytochrome P 450 CYP11B1, Steroid 11 beta Hydroxylase, Steroid 11 beta Monooxygenase
  • Steroid 12-alpha-Hydroxylase - »õâ A liver microsomal cytochrome P450 enzyme that catalyzes the 12-alpha-hydroxylation of a broad spectrum of sterols in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP8B1gene, converts 7-alpha-hydroxy-4-cholesten-3-one to 7-alpha-12-alpha-dihydroxy-4-cholesten-3-one and is required in the synthesis of BILE ACIDS from cholesterol.
    Synonyms : 12alpha-Hydroxylase, CYP8B1, Cytochrome P450 8B1, Cytochrome P450 CYP8B1, Steroid 12-Hydroxylase, Steroid-12-Hydroxylase, Steroid-12-Monooxygenase, Sterol 12 alpha-Hydroxylase, 12 alpha Hydroxylase, 12 alpha-Hydroxylase, Sterol, 12alpha Hydroxylase
  • Steroid 16-alpha-Hydroxylase - »õâ A liver microsomal cytochrome P450 enzyme that catalyzes the 16-alpha-hydroxylation of a broad spectrum of steroids, fatty acids, and xenobiotics in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme is encoded by a number of genes from several CYP2 subfamilies.
    Synonyms : 16-alpha Hydroxylase, 16alpha-Hydroxylase, Estradiol 16-alpha Hydroxylase, Estrogen 16-alpha Hydroxylase, Estrone 16-alpha Hydroxylase, Estrone-3-sulfate 16-alpha Hydroxylase, Progesterone 16 alpha-Hydroxylase, Progesterone 16-alpha-Hydroxylase
  • Steroid 17-alpha-Hydroxylase - »õâ A microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pregnenolone and subsequent cleavage of the residual two carbons at C17 in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP17 gene, generates precursors for glucocorticoid, androgen, and estrogen synthesis. Defects in CYP17 gene cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL) and abnormal sexual differentiation.
    Synonyms : 17 alpha-Hydroxylase Cytochrome P-450, 17 alpha-Hydroxyprogesterone Aldolase, 17, 20-Desmolase, Cytochrome P-450(17-alpha), Cytochrome P450(17 alpha), Hydroxyprogesterone Aldolase, Steroid 17 alpha-Hydroxylase, Steroid-17-Hydroxylase, 17 alpha Hydroxylase
  • Steroid 21-Hydroxylase - »õâ An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
    Synonyms : 21-Hydroxylase, Cytochrome P-450 21-Hydroxylase, Cytochrome P-450 c21, Cytochrome P-450(c-21), Cytochrome P450c21, Progesterone 21-Hydroxylase, Steroid-21-Hydroxylase, 21 Hydroxylase, Cytochrome P 450 21 Hydroxylase, Cytochrome P 450 CYP21, Cytochrome P 450 c21
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MeSH(Medical Subject Headings) À¯»ç °Ë»ö (http://www.nlm.nih.gov) °á°ú : 0 ÆäÀÌÁö: 19
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