| ectoprotein kinase | <enzyme> From outer plasma membranes; active site and substrate oriented extracellularly Registry number: EC 2.7.1.- Synonym: ecto-protein kinase, ectokinase (26 Jun 1999) |
|---|---|
| TIE-2 receptor tyrosine kinase | <enzyme> Expressed in developing vascular endothelial cells; unlike tie-1, also expressed in lens epithelium and heart epicardium; has the same organization of amino acid sequence motifs characteristic of tie-1; aa sequence of the intracellular and extracellular regions of tie-1 and tie-2 are 79% and 32% identical, respectively; aa sequence of both kinases given in first source Registry number: EC 2.7.10.- Synonym: tie-2-rtk (26 Jun 1999) |
| tie receptor tyrosine kinase | <enzyme> From human leukaemia cells; expressed in developing vascular endothelial cell; has homology with egf, bfgf, csf-1, pdgf and stem cell factor receptors; ligand and biologic function not known as of 12/92; tie-1 receptor tyrosine kinase is rat homolog of tie receptor tyrosine kinase; aa sequence known Registry number: EC 2.7.10.- Synonym: tie-1 receptor tyrosine kinase, tie-1 rtk (26 Jun 1999) |
| eif-2 kinase | <enzyme> A dsrna-activated camp-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsrna and ATP, eif-2 kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyses the phosphorylation of the alpha subunit of eif-2, leading to the inhibition of protein synthesis. Registry number: EC 2.7.10.- (12 Dec 1998) |
| tropomyosin kinase | <enzyme> From chick embryo; requires mg; ca and cyclic AMP not needed Registry number: EC 2.7.1.132 (26 Jun 1999) |
| TTK kinase | <enzyme> Can phosphorylate serine, threonine and tyrosine hydroxyamino acids and is associated with cell proliferation; amino acid sequence given in first source Registry number: EC 2.7.10.- (26 Jun 1999) |
| estradiol receptor tyrosine kinase | <enzyme> Calcium and calmodulin dependent Registry number: EC 2.7.1.- Synonym: ertk (26 Jun 1999) |
| tyrosine kinase | <enzyme> Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand binding domain, a single transmembrane domain and an intracellular tyrosine kinase domain and nonreceptor tyrosine kinases, which are soluble, cytoplasmic kinases. (18 Nov 1997) |
| tyrosyl tRNA synthetase kinase | <enzyme> From postribosomal supernatants of bom:nmri mouse liver; comigrates with tyrosyl trna synthetase during several purification steps Registry number: EC 2.7.1.- Synonym: tyr trna synthetase kinase (26 Jun 1999) |
| kanamycin kinase | <enzyme> A class of enzymes that inactivate aminoglycoside-aminocyclitol antibiotics by regiospecific phosphorylation of the 3' and/or 5' hydroxyl. Chemical name: ATP:kanamycin 3'-O-phosphotransferase Registry number: EC 2.7.1.95 (12 Dec 1998) |
| Yrk kinase | <enzyme> Non-receptor type protein kinase of src family; consists of 536 amino acids and has all the canonical features of a src kinase; expressed at elevated levels in neuronal and haematopoietic tissues; amino acid sequence given in first source Registry number: EC 2.7.1.- Synonym: yes-related kinase, yrk protein (26 Jun 1999) |
| YRP kinase | <enzyme> Yrp - tyrosine-regulated protein kinase; activated by v-src and protein kinase c-mediated signal transduction pathways Registry number: EC 2.7.10.- (26 Jun 1999) |
| YSK1 kinase | <enzyme> Ysk1 - yeast sps1/ste20-related kinase 1; a mammalian kinase structurally related to ste20 and sps1 but not involved in known mapk pathways; amino acid sequence given in first source Registry number: EC 2.7.10.- (26 Jun 1999) |
| Fas-activated serine-threonine kinase | <enzyme> Phosphorylates tia-1 during fas-mediated apoptosis; contains proline-rich sh3-binding domains; mw 60-63 kD; genbank x86779 Registry number: EC 2.7.10.- Synonym: fast kinase (26 Jun 1999) |
| ZAP-70 kinase | <enzyme> Associated with the t-cell receptor zeta chain; amino acid sequence given in first source Registry number: EC 2.7.1.- Synonym: zap-70 protein, zap-70 gene product (26 Jun 1999) |