| leupeptin acid synthetase | <enzyme> ATP essential for reaction Registry number: EC 6.3.2.- (26 Jun 1999) |
|---|---|
| leupeptinase | <enzyme> Serine protease active at neutral pH; inhibited by isoflurophate and phenylmethylsulfonyl fluoride Registry number: EC 3.4.21.- (26 Jun 1999) |
| leupeptins | <chemical> A group of acylated oligopeptides produced by actinomycetes that function as protease inhibitors. They have been known to inhibit to varying degrees trypsin, plasmin, kallikrein, papain and the cathepsins. Pharmacological action: protease inhibitors. (12 Dec 1998) |
| leuprolide | <chemical> A synthetic nonapeptide agonist analog of gonadorelin. It is used in the treatment of advanced prostatic cancer, fibrocystic disease of the breast, and leiomyoma of the uterus. Pharmacological action: antineoplastic agent, hormonal. Chemical name: Luteinizing hormone-releasing factor (pig), 6-D-leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide- (12 Dec 1998) |
| leuprolide acetate | A synthetic nonapeptide analog of naturally occurring gonadotropin-releasing hormone; used in the palliative treatment of advanced prostatic cancer. (05 Mar 2000) |
| leurocristine | A dimeric alkaloid obtained from Vinca rosea; its antineoplastic activity is similar to that of vinblastine, but no cross-resistance develops between these two agents, and it is more useful than vinblastine in lymphocytic lymphosarcoma and acute leukaemia. Synonym: leurocristine. (05 Mar 2000) |