| glutaral |
glutaraldehyde.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
|
|---|---|
| glutaraldehyde f. |
a fixative used in specimen preparation for electron microscopy that does not simultaneously stain the tissue.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
|
| glutaric acid |
a dicarboxylic acid occurring at high levels in the blood and urine in glutaricaciduria.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
|
| glutaricacidemia |
1. glutaricaciduria (def. 1). 2. an excess of glutaric acid in the blood.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
|
| glutaricaciduria |
1. an autosomal recessive aminoacidopathy characterized by accumulation and excretion of glutaric acid in the urine. It occurs in two types: Type I is due to deficiency of glutaryl-CoA dehydrogenase and is characterized by excretion also of 3-hydroxyglutaric acid, progressive dystonia and dyskinesia, hypoglycemia, mild ketosis and acidosis, opisthotonus, choreoathetosis, motor delay, mental retardation, hypotonia, and death within the first decade. Type II is due to deficiency of either electron transfer flavoprotein (α-subunit) or electron transfer flavoprotein:ubiquinone oxidoreductase and is characterized by accumulation and excretion of glutaric and 2-hydroxyglutaric acids as well as multiple organic acids normally oxidized by mitochondrial flavin-containing acyl-CoA dehydrogenases, which require both proteins for activity. Additional manifestations include hypoglycemia without ketosis, metabolic acidosis, and a spectrum of phenotypic manifestations varying with the particular defect. Increasing age of onset is correlated with decreasing severity; when of neonatal onset it may be accompanied by congenital anomalies and is rapidly fatal. Type II is called also multiple acyl CoA dehydrogenation deficiency. 2. excretion of glutaric acid in the urine.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
|