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cell line, transformed Eukaryotic cell line obtained in a quiescent or stationary phase which undergoes conversion to a state of unregulated growth in culture, resembling an in vitro tumour. It occurs spontaneously or through interaction with viruses, oncogenes, radiation, or drugs/chemicals.
(12 Dec 1998)
cell locomotion <cell biology> Movement of a cell from one place to another.
(26 Mar 1998)
cell marker <cell biology> Biochemical or genetic characteristics which distinguish and discriminate between different cell types.
(26 Mar 1998)
cell matrix A fluid cytoplasmic substance filling the interstices of the cytoskeleton.
Synonym: cell matrix, cytomatrix.
(05 Mar 2000)
cell-mediated immunity <immunology> Immune response that involves effector T lymphocytes and not the production of humoral antibody.
Responsible for allograft rejection, delayed hypersensitivity and in defence against viral infection and intracellular protozoan parasites.
(26 Mar 1998)
cell-mediated reaction Immunological reaction of the delayed type, involving chiefly T lymphocytes, important in host defense against infection, in autoimmune diseases, and in transplant rejection.
See: skin test.
(05 Mar 2000)
cell membrane <cell biology> The structure enveloping a cell, enclosing the cytoplasm and forming a selective permeability barrier.
It consists of lipids, proteins and some carbohydrates, the lipids thought to form a bilayer in which integral proteins are embedded to varying degrees.
Synonym: plasma membrane.
(26 Mar 1998)
cell membrane permeability A quality of cell membranes which permits the passage of solvents and solutes into and out of cells.
(12 Dec 1998)
cell migration <cell biology> Implies movement of a population of cells from one place to another as in the movement of neural crest cells during morphogenesis.
(26 Mar 1998)
cell migration inhibition Phenomenon of cell-mediated immunity measured by in vitro inhibition of the migration or phagocytosis of antigen-stimulated leukocytes or macrophages. Specific assays have been developed to estimate levels of migration-inhibitory factor, immune reactivity against tumour-associated antigens, and immunosuppressive effects of infectious microorganisms.
(12 Dec 1998)
cell movement <cell biology> A more general term than locomotion, that can include shape change, cytoplasmic streaming etc.
(26 Mar 1998)
cell nucleolus Within most types of eukaryotic cell nucleus, a distinct region, not delimited by a membrane, in which some species of rrna (RNA, ribosomal) are synthesised and assembled into ribonucleoprotein subunits of ribosomes. In the nucleolus rrna is transcribed from a nucleolar organiser, i.e., a group of tandemly repeated chromosomal genes which encode rrna and which are transcribed by RNA polymerase I.
(12 Dec 1998)
cell nucleus Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (cell nucleolus). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the endoplasmic reticulum. A cell may contain more than one nucleus.
(12 Dec 1998)
P cell A characteristic specialised cell, with probable pacemaker function, found in the S-A node and A-V junction.
(05 Mar 2000)
cell organelle <cell biology> A structurally discrete component of a cell.
(18 Nov 1997)
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