| T(O) | oral temperature |
|---|---|
| TOPV | trivalent oral poliovaccine |
| PAS | 1) Periodic Acid-Schiff Stain 2) Para-Amino-Salicyclic Acid &nbs... |
| AHA | acetohydroxamic acid; acquired hemolytic anemia; acute hemolytic anemia; American Heart Association;... |
| AP | accessory pathway; accounts payable; acid phosphatase; acinar parenchyma; action potential; active p... |
| d(-)-alpha-aminobenzylpenicillin | <drug> Penicillin derivative with broad spectrum activity, ampicillin resistance is often used as a marker for plasmid transfer in genetic engineering (for example pBR322 is ampicillin resistant). (13 Nov 1997) |
|---|---|
| deficiency, alpha-1 antitrypsin | An inherited disease with little or no production of an important protein, alpha-1 antitrypsin. The lack of this protein leads to damage of various organs, mainly the lung and liver. The disease may become apparent at a very early age or in adulthood, as shortness of breath or liver-related symptoms (jaundice, fatigue, fluid in the abdomen, mental changes, or gastrointestinal bleeding). There are several options for treatment of the lung disease, including replacement of the missing protein. Treatment of the liver disease is a well-timed liver transplant (12 Dec 1998) |
| delta-(alpha-aminoadipyl)cysteinylvalinedisulfide reductase | <enzyme> Broad range disulfide reductase from streptomyces clavuligerus; requires NADPH; involved in the production of beta-lactam antibiotic such as penicillins and cephalosporins Registry number: EC 1.6.4.- Synonym: bis-acv reductase, delta-(-l-alpha-aminoadipyl)-l-cysteinyl-d-valine disulfide reductase, acv disulfide reductase (26 Jun 1999) |
| dextrin 6-alpha-d-glucosidase | <enzyme> Catalyses endohydrolysis of 1,6-alpha-d-glucoside linkages at points of branching in chains of 1,4-linked alpha-d-glucose residues Registry number: EC 3.2.1.33 (26 Jun 1999) |
| diadenosine 5,5'''-P(1),P(4)-tetraphosphate alpha,beta-phosphorylase | <enzyme> Ap4a + inorganic po4 forms ATP + ADP Registry number: EC 2.7.7.53 Synonym: ap4a phosphorylase, ATP adenylyltransferase (26 Jun 1999) |
| dihydrostreptomycin-6-phosphate 3' alpha-kinase | <enzyme> Catalyses the phosphorylation of dihydrostreptomycin 6-phosphate in the 3'-position in the presence of ATP Registry number: EC 2.7.1.88 Synonym: dihydrostreptomycin-6-p 3' alpha-kinase (26 Jun 1999) |
| dolichyl-phosphate alpha-N-acetylglucosaminyltransferase | <enzyme> Combined with EC 2.4.1.141 forms chitobiosylpyrophosphoryldolichol synthase Registry number: EC 2.4.1.153 Synonym: dpagtransferase (26 Jun 1999) |
| dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase | <enzyme> Catalyses the transfer of mannose from dolichyl-p-mannose to the man(5)(glcnac)2-pp-dolichol acceptor glycolipid Registry number: EC 2.4.1.130 Synonym: dolichyl-p-mannose-dolichyl-pp-heptasaccharide alpha-mannosyltransferase, dolichyl-p-mannose-man(5)(glcnac)2-pp-dolichol mannosyltransferase, dpm-g-mannosyltransferase (26 Jun 1999) |
| D-selenocystine alpha, beta-lyase | <enzyme> From clostridium sticklandii; pyridoxal-p enzyme; mw 74kda; decomposes d-selenocystine into pyruvate, nh3 and elemental selenium; d-cystine, d-lanthionine, meso-lanthionine and d-cysteine can also serve as substrates; d-selenocysteine, d-serine, dl-selenohomocystine and l-amino acids are inert Registry number: EC 4.99.- Synonym: dsc-ab-lyase (26 Jun 1999) |
| I kappa B alpha-associated protein kinase | <enzyme> Isolated from human monocytic cell line; phosphorylates ser(293), ser(288), and thr(291) of ikappabalpha Registry number: EC 2.7.10.- Synonym: ikappabalpha-associated protein kinase, ikappab-alpha-associated protein kinase, ikappabalpha kinase (26 Jun 1999) |
| immunoglobulins, alpha-chain | Heavy chains found in the fab and fc fragments of IgA and having a molecular weight of approximately 58 kD. They contain about 470 amino acid residues arranged in four domains and an oligosaccharide component bound covalently to the fc fragment. (12 Dec 1998) |
| indolyl-3-alkane-alpha-hydroxylase | <enzyme> Indoyl-3-alkane-alpha-hydroxylase; haemprotein which needs no cofactor Registry number: EC 1.13.99.- Synonym: tryptophan side chain oxidase (26 Jun 1999) |
| inositol 1-alpha-galactosyltransferase | <enzyme> Catalyses conversion of udpgalactose plus myo-inositol to galactinol plus udp Registry number: EC 2.4.1.123 Synonym: galactinol synthase (26 Jun 1999) |
| inter-alpha-inhibitor | <chemical> Inhibits bovine trypsin and chymotrypsin; complex formed with chymotrypsin less stable; alpha-glycoprotein; shap - serum-derived hyaluronan associated protein Pharmacological action: serine proteinase inhibitors, trypsin inhibitors Chemical name: trypsin inhibitor, inter-alpha- Synonym: inter-alpha-trypsin inhibitor, protein pi, inter-alpha-trypsin inhibitor, heavy chain, shap protein (05 Dec 1998) |
| interferon-alpha | <cytokine> One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells when exposed to live or inactivated virus, double-stranded RNA, or bacterial products. It is the major interferon produced by virus-induced leukocyte cultures and, in addition to its pronounced antiviral activity, causes activation of NK cells. It is used experimentally in the treatment of hairy-cell leukaemia. A number of different subtypes exist that are elaborated by leukocytes in response to viral infection or stimulation with double-stranded RNA; IFN-alpha-2A and -2B are protein products made by recombinant DNA techniques and are used as antineoplastic agents. See: interferon-alpha 2a, interferon-alpha 2b Synonym: leukocyte interferon. Pharmacological action: antineoplastic agent, antiviral agent. (20 Sep 2002) |