| amidonaphthol red | An azo dye, C18H13N3S2Na2, used in light and fluorescence microscopy as a real acid counterstain. Synonym: azophloxin. (05 Mar 2000) |
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| amidophosphoribosyltransferase | <enzyme> An enzyme, involved in the early steps of purine nucleotide biosynthesis, that catalyses the formation of 5-phosphoribosylamine from glutamine and phosphoribosylpyrophosphate. Chemical name: 5-Phosphoribosylamine:pyrophosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating) Registry number: EC 2.4.2.14 (12 Dec 1998) |
| amidopyrine | <chemical> A drug with analgesic, anti-inflammatory, and antipyretic properties but, owing to the risk of agranulocytosis, whose use is discouraged. Pharmacological action: non-steroidal anti-inflammatory agents. Chemical name: 3H-Pyrazol-3-one, 4-(dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl- (12 Dec 1998) |
| Amidostomum anseris | A species of bloodsucking nematodes, similar to those of the genus Trichostrongylus, that parasitises the gizzard and sometimes also the proventriculus and oesophagus of domestic and wild ducks and geese; it causes heavy mortality in young birds. Origin: amido-+ G. Stoma, mouth, + L. Anser, goose (05 Mar 2000) |
| amidoximes | The oximes of amides with the general formula, R-C(NH2)-NOH. Synonym: amide oximes. (05 Mar 2000) |
| amidoxyl | The radical of an amide oxime (amidoxime), the terminal H (of the NOH) having been lost. (05 Mar 2000) |
| amifostine | <chemical> 2-((3-aminopropyl)amino)ethanethiol dihydrogen phosphate (ester). A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia. Pharmacological action: radiation-protective agents. Chemical name: Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester) (12 Dec 1998) |
| amikacin | <chemical> O-3-amino-3-deoxy-alpha-d-glucopyranosyl-(1-6)-o-(6-amino-6-deoxy-alpha-d-glucopyranosyl-(1-4)-n(1)-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-d-streptamine. A broad-spectrum antibiotic derived from kanamycin. It is reno- and ototoxic like the other aminoglycoside antibiotics. Pharmacological action: antibiotics, aminoglycoside. Chemical name: D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1-4))-N1-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-, (S)- (12 Dec 1998) |
| amikacin sulfate | An aminoglycoside antibiotic agent with antimicrobial activity similar to that of kanamycin; also effective against Pseudomonas aeruginosa. (05 Mar 2000) |
| amiloride | <drug> A drug that blocks sodium/proton antiport, used clinically as a potassium sparing diuretic. (18 Nov 1997) |
| amiloride hydrochloride | N-Amidino-3,5-diamino-6-chloropyrazinecarboxami de monohydrochloride dihydrate;a non-steroidal compound exerting an effect similar to that of an aldosterone inhibitor, i.e., urinary sodium excretion is enhanced and potassium excretion is reduced; a potassium sparing diuretic. (05 Mar 2000) |
| amimia | 1. Inability to express ideas by nonverbal communication, such as gestures or signs. 2. Asymbolia; the inability to comprehend the meaning of gestures, signs, symbols, or pantomime. Origin: G. A-priv. + minos, a mimic (05 Mar 2000) |
| aminacrine | <chemical> Highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used as intracellular pH indicator. Pharmacological action: anti-infective agents, local, fluorescent dyes, indicators and reagents, mutagens. Chemical name: 9-Acridinamine (12 Dec 1998) |
| aminacrine hydrochloride | Bactericidal agent for external use. See: acridine yellow. Synonym: 5-aminoacridine hydrochloride, 9-aminoacridine hydrochloride. (05 Mar 2000) |
| aminate | To combine with ammonia. (05 Mar 2000) |