| accustomable | Habitual; customary; wonted. "Accustomable goodness." Source: Websters Dictionary (01 Mar 1998) |
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| accustomably | According to custom; ordinarily; customarily. Source: Websters Dictionary (01 Mar 1998) |
| accustomance | Custom; habitual use. Origin: OF. Accoustumance, F. Accoutumance. Source: Websters Dictionary (01 Mar 1998) |
| accustomarily | Customarily. Source: Websters Dictionary (01 Mar 1998) |
| accustomary | Usual; customary. Source: Websters Dictionary (01 Mar 1998) |
| accustomed | 1. Familiar through use; usual; customary. "An accustomed action." 2. Frequented by customers. "A well accustomed shop." Source: Websters Dictionary (01 Mar 1998) |
| accustomedness | Habituation. "Accustomedness to sin hardens the heart." (Bp. Pearce) Source: Websters Dictionary (01 Mar 1998) |
| ACE | <enzyme> This hydrolase enzyme cleaves the decapeptide angiotensin I (biologically inactive) to form active angiotensin II by angiotensin-converting enzyme which removes a dipeptide (histidylleucine) from angiotensin I. Angiotensin II causes contraction of vascular smooth muscle and thus raises blood pressure and stimulates aldosterone release from the adrenal glands. Angiotensin is finally broken down by angiotensinases. Elevations in angiotensin converting enzyme are seen sarcoidosis, histoplasmosis, alcoholic cirrhosis, asbestosis, berylliosis, diabetes, Hodgkin's disease, hyperthyroidism, amyloidosis, primary biliary cirrhosis, idiopathic pulmonary fibrosis, pulmonary embolism, scleroderma, silicosis, tuberculosis, Gaucher's disease and leprosy. The normal values are 18 to 67 U/ml over 20 years of age (people under 20 have higher levels). Drugs that inhibit ACE are used to treat hypertension and congestive heart failure. See: angiotensin-converting enzyme inhibitor Acronym: ACE (12 Aug 2000) |
| ACE inhibitor | <pharmacology> A group of antihypertensive medications that work by inhibiting an enzyme (angiotensin-converting enzyme) that is important in the regulation of blood pressure. Studies have also indicated that it may help prevent or slow the progression of kidney disease in patients with diabetes. Examples include: captopril, ramipril, enalapril, losartan potassium, bepridil and lisinopril. (12 Mar 1998) |
| ACE level | <investigation> This is a blood test which measures the concentration of angiotensin-converting enzyme (ACE) in the bloodstream. Elevations in angiotensin-converting enzyme are seen sarcoidosis, histoplasmosis, alcoholic cirrhosis, asbestosis, berylliosis, diabetes, Hodgkin's disease, hyperthyroidism, amyloidosis, primary biliary cirrhosis, idiopathic pulmonary fibrosis, pulmonary embolism, scleroderma, silicosis, tuberculosis, Gaucher's disease and leprosy. The normal values are 18 to 67 U/ml over 20 years of age (people under 20 have higher levels). (15 Jan 1998) |
| acebutolol | <chemical> N-(3-acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)butanamide. A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action. Pharmacological action: adrenergic beta-antagonists, anti-arrhythmia agents, antihypertensive agents, sympatholytics. Chemical name: Butanamide, N-(3-acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)-, (+-)- (12 Dec 1998) |
| acecainide | <chemical> 4-(acetylamino)-n-(2-(diethylamino)ethyl)benzamide. Major metabolite of procainamide. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure. Pharmacological action: anti-arrhythmia agents. Chemical name: Benzamide, 4-(acetylamino)-N-(2-(diethylamino)ethyl)- (12 Dec 1998) |
| aceclidine | 3-Quinuclidinol acetate ester;a cholinergic drug used for topical therapy of glaucoma. (05 Mar 2000) |
| acedapsone | <chemical> Acetylated sulfone that is slowly metabolised to give long-term, low blood levels of dapsone. It has antimicrobial and antimalarial action, but is mainly used as a depot leprostatic agent. Pharmacological action: anti-infective agents, antimalarials, leprostatic agents. Chemical name: Acetamide, N,N'-(sulfonyldi-4,1-phenylene)bis- (12 Dec 1998) |
| acedia | A mental syndrome, the chief features of which are listlessness, carelessness, apathy, and melancholia. (05 Mar 2000) |