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ribonucleoside diphosphate reductase [EC 1.17.4.1] an enzyme of the oxidoreductase class that catalyzes the formation of 2′-deoxyribonucleotides from the corresponding ribonucleoside diphosphates using NADPH as the ultimate electron donor. The deoxyribonucleoside diphosphates are used in DNA synthesis. Called also ribonucleotide reductase.
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ribopyranose ribose occurring in the cyclic pyranose configuration; it is the usual form in solution although not in ribonucleic acids.
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ribose n. a ribonucleic acid–protein complex.
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ribose-5-phosphate isomerase [EC 5.3.1.6] an enzyme of the isomerase class that catalyzes the interconversion of ribulose 5-phosphate and ribose 5-phosphate. The reaction is part of the pentose phosphate pathway and is important in ribose metabolism.
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ribose-phosphate pyrophosphokinase [EC 2.7.6.1] an enzyme of the transferase class that catalyzes the phosphorylation of ribose 5-phosphate to form phosphoribosylpyrophosphate, the initial reactant in purine and pyrimidine nucleotide biosynthesis. Enhanced enzyme activity, an X-linked recessive trait, leads to increased purine synthesis and causes primary gout. Called also phosphoribosylpyrophosphate synthetase.
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