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  • Leukotriene A4 - »õâ (2S-(2 alpha,3 beta(1E,3E,5Z,8Z)))-3-(1,3,5,8-Tetradecatetraenyl)oxiranebutanoic acid. An unstable allylic epoxide, formed from the immediate precursor 5-HPETE via the stereospecific removal of a proton at C-10 and dehydration. Its biological actions are determined primarily by its metabolites, i.e., LEUKOTRIENE B4 and cysteinyl-leukotrienes. Alternatively, leukotriene A4 is converted into LEUKOTRIENE C4 by glutathione-S-transferase or into 5,6-di-HETE by the epoxide-hydrolase. (From Dictionary of Prostaglandins and Related Compounds, 1990)
    Synonyms : Leukotriene A, Leukotriene A-4, Leukotrienes A, Leukotriene A 4
  • Leukotriene Antagonists - »õâ A class of drugs designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level.
    Synonyms : Antagonists, Leukotriene, Receptor Antagonists, Leukotriene, Antagonists, Leukotriene Receptor
  • Leukotriene B4 - »õâ The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990)
    Synonyms : Leukotriene B, Leukotriene B-4, Leukotrienes B, 5, 12 HETE, 5, 12 diHETE, B-4, Leukotriene, Leukotriene B 4
  • Leukotriene C4 - »õâ The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular smooth muscle. (From Dictionary of Prostaglandins and Related Compounds, 1990)
    Synonyms : Leukotriene C, Leukotriene C-1, Leukotriene C-4, Leukotriene C1, Leukotrienes C, Leukotriene C 1, Leukotriene C 4
  • Leukotriene D4 - »õâ One of the biologically active principles of SRS-A. It is generated from LEUKOTRIENE C4 after partial hydrolysis of the peptide chain, i.e., cleavage of the gamma-glutamyl portion. Its biological actions include stimulation of vascular and nonvascular smooth muscle, and increases in vascular permeability. (From Dictionary of Prostaglandins and Related Compounds, 1990)
    Synonyms : Leukotriene D, Leukotriene D-4, Leukotrienes D, Leukotriene D 4
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leukemia A progressive, malignant disease of the blood-forming tissues, marked by an excessive number of white blood cells and their precursors. Ligand
Ãâó: www.electric-words.com/cell/csiro/glossary.html
leukocyte (white blood cell, WBC) - a group of small colorless blood cells, which play a major role in the body's immune system. There are five basic white blood cells: monocytes, lymphocytes, neutrophils, eosinophils and basophils.
Ãâó: www.night-thunder.com/diseaseglossary.html
leukocyte the term used for all types of white blood cells (granulocyte, lymphocyte, monocyte) Among the functions of the leukocyte are the engulfment of bacteria, fungi and viruses.
Ãâó: www.yourbloodcenter.org/glossary.htm
leukemia The uncontrolled growth of white bloods cells in bone marrow, often overflowing to the circulating blood. As cancers of white blood cells, some leukemias and lymphomas are related; some are distinguished from each other only by their relative presence in marrow versus lymph nodes.
Ãâó: www.patientcenters.com/lymphoma/news/nhl7.html
leukocytosis A condition characterized by an abnormally high total number of circulating leukocytes.
Ãâó: www.bloodmobile.org/glossary.html
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