| 3 beta-hydroxy-delta 5-C(27)-steroid dehydrogenase | <enzyme> Second enzyme in the sequence that converts cholesterol to bile acids; deficiency leads to chronic liver disease in childhood Registry number: EC 1.1.1.- Synonym: 7 alpha-hydroxycholesterol 3 beta-dehydrogenase, 7-hydroxycholesterol 3-dehydrogenase, 3 beta-hydroxy-delta(5)-c(27)-steroid oxidoreductase, 5-cholestene-3beta,7alpha-diol oxidase (26 Jun 1999) |
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| 3 beta-hydroxysteroid oxidoreductase-delta(5) 3-ketosteroid isomerase | <chemical> System found in breast cancers; consists of EC 1.1.1.145 (progesterone reductase) and EC 5.3.3.1 (steroid delta-isomerase)) Synonym: 3 ohsteroid dehydrogenase-isomerase, delta 5-3 beta hydroxysteroid dehydrogenase-isomerase, 3 beta-hydroxysteroid dehydrogenase-isomerase, 3 beta-hydroxysteroid dehydrogenase-delta(5)-delta(4)-isomerase, 3 beta-hydroxysteroid dehydrogenase-5--4-ene-isomerase, 3-beta-hydroxysteroid dehydrogenase-delta(5-4)-isomerase, 3 beta hydroxysteroid dehydrogenase-delta5-delta4-isomerasease, 3 beta-ol dehydrogenase-delta(4)-delta(5) isomerase, 3 beta-hydroxy-5-ene steroid dehydrogenase-delta 5-delta 4 isomerase (26 Jun 1999) |
| 3 (or 17)-beta-hydroxysteroid dehydrogenase | <enzyme> Acts on both 3 beta or 17 beta hydroxysteroids; 17 beta type 1 is probably estradiol dehydrogenases; for 3 or 17 alpha-hydroxysteroids see EC 1.1.1.209; was mapped to testosterone dehydrongenases (85-93) (see under 17-hydroxysteroid dehydrogenases (85-90); on-line search 17-hydroxysteroid dehydrogenases (85-93), index medicus search testosterone dehydrogenases (91-93), 17-hydroxysteroid dehydrogenases (85-90) Registry number: EC 1.1.1.51 Synonym: 3 beta,17 beta-hydroxysteroid dehydrogenase, 3,17-beta-hsdase, 17beta-hydroxysteroid dehydrogenase, 17beta hsd1 (26 Jun 1999) |
| 3-oxo-5 beta-steroid delta 4-dehydrogenase | <enzyme> Do not confuse with EC 1.3.1.23 (cholestenone 5 beta-reductase) which is also steroid 5 beta-reductase in chemline; do not use for enzyme using NADP-see EC 1.3.1.23 and EC 1.3.1.3 Chemical name: 3-oxo-5 beta-steroid delta(4)dehydrogenase Registry number: EC 1.3.99.6 Synonym: steroid 5 beta-reductase, testosterone 5 beta-reductase, 4-ene-5 beta-reductase, delta(4)-3-ketosteroid-5 beta-(acceptor)-reductase, testosterone 5beta-reductase, delta(4)-5beta-reductase, cytosolic 4-ene-reductase (26 Jun 1999) |
| 4-androstene-3,17-dione-16 beta-hydroxylase | <enzyme> Catalyses androst-4-en-3,17-dione to 16 beta-hydroxyandrost-4-en-3,17-dione; cytochrome p450 2b1 is both a androstenedione 16beta-hydroxylase and a testosterone 16beta-hydroxylase Registry number: EC 1.14.99.- Synonym: aedo-16-hydroxylase, steroid 16-hydroxylase, cytochrome p450 2b2, cyp 2b2, cyp2b2 (26 Jun 1999) |
| 4-methylumbelliferyl-beta-galactosidase | <enzyme> Non-specific brain enzyme; distinct from EC 3.2.1.46 Registry number: EC 3.2.1.- Synonym: 4-mub-galactosidase (26 Jun 1999) |
| 4-methylumbelliferyl-beta-glucosidase | <enzyme> Aspect of EC 3.2.1.21 Registry number: EC 3.2.1.- (26 Jun 1999) |
| 4-methylumbelliferyl-tetra-N-acetyl-beta-D-chitotetraoside hydrolase | <enzyme> Not identical to human plasma lysozyme Registry number: EC 3.2.1.- Synonym: mu-tact hydrolase (26 Jun 1999) |
| 4-nitrophenyl beta-galactoside hydrolase | <enzyme> From biomphalaria glabrata; does not act on galactans Registry number: EC 3.2.1.- Synonym: para-nitrophenyl beta-galactoside hydrolase, 4-nitrophenyl-beta-d-galactosidase (26 Jun 1999) |
| 5 beta-cholestane-3 alpha,7 alpha-diol 26-hydroxylase | <enzyme> Nadp-dependent Registry number: EC 1.14.13.- (26 Jun 1999) |
| 6-ethanoylamino-4-methylumbelliferyl-beta-glucosidase | <enzyme> A soluble lysosomal enzyme with a discrete isoelectric point of about 5.0; hydrolyzes 6-ethanoylamino-4-methylumbelliferyl-beta-d-glucoside Registry number: EC 3.2.1.- Synonym: emglc-ase (26 Jun 1999) |
| 6-phospho-beta-glucosidase | <enzyme> Catalyses the conversion of 6-phospho-beta-d-glucosyl-(1,4)-d-glucose and h2o to d-glucose-6-phosphate and d-glucose; do not confuse with bgla gene product from rhodothermus which catalyses the reaction of EC 3.2.1.39 (endo-1,3-beta-glucanase) Registry number: EC 3.2.1.86 Synonym: bgla gene product, bglh gene product, glvg gene product (26 Jun 1999) |
| 7 beta-hydroxysteroid dehydrogenase | <enzyme> Nadp-dependent Registry number: EC 1.1.1.- Synonym: 7beta-hos dh, 7beta-hydroxysteroid dehydrogenase (26 Jun 1999) |
| 9-beta-d-ribofuranosyladenine | <biochemistry> A ribonucleotide which consists of the nitrogenous base adenine linked to the sugar ribose. <drug> A cardiac drug used in terminating PSVT involving reentry pathways that include the AV node or Wolff-Parkinson-White syndrome. For atrial flutter, atrial fibrillation, atrial or ventricular tachycardias, adenosine may produce transient AV block that may help identify the rhythm. Pharmacologic action: Endogenous purine nucleoside that depresses AV node and sinus node activity. Brief duration of action (1-2 min). Dose: Rapid 6 mg IV bolus over 1-3 sec. May repeat at 12 mg IV bolus within 1-2 min Patients taking theophylline may require larger doses. Use a smaller dose with cardiac transplant patients. Potential complications: Common but transient - flushing, dyspnea, chest pain, bradycardia, and ventricular ectopy. Theophylline (and caffeine) blocks adenosine's effects. Dipyridamole potentiates adenosine's effects. Use other agents to avoid these drug interactions. (15 Mar 2000) |
| 9-beta-d-ribofuranosylguanine | <biochemistry, molecular biology> The nucleoside formed by linking ribose to guanine. (18 Nov 1997) |