| diseases, single-gene | Hereditary disorders caused by a change (mutation) in a single gene. There are thousands of single-gene diseases including achondroplastic dwarfism, Huntington disease, cystic fibrosis, sickle cell disease, Duchenne muscular dystrophy, and haemophilia. Single-gene diseases typically describe classic simple Mendelian patterns of inheritance (as autosomal dominant, autosomal recessive, and X-linked traits) by comparison with polygenic diseases. (12 Dec 1998) |
|---|---|
| dog diseases | Diseases of the domestic dog (canis familiaris). This term does not include diseases of wild dogs, wolves, foxes, and other canidae for which the heading carnivora is used. (12 Dec 1998) |
| ileal diseases | Diseases of the ileum including the ileocaecal valve. (12 Dec 1998) |
| immune complex diseases | Diseases characterised by the presence of immune complexes in body fluids. Hypersensitivity of the Arthus type and serum sickness are examples. (18 Nov 1997) |
| immune deficiency diseases | Those diseases in which immune reactions are suppressed or reduced. Reasons may include congenital absence of B and/or T lymphocytes or viral killing of helper lymphocytes (see HIV). (18 Nov 1997) |
| immunologic diseases | Disorders caused by abnormal or absent immunologic mechanisms, whether humoral, cell-mediated or both. (12 Dec 1998) |
| infant, newborn, diseases | Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both hereditary diseases and metabolism, inborn errors are available as general concepts. (12 Dec 1998) |
| inflammatory bowel diseases | Chronic, non-specific disorders of unknown aetiology. Includes crohn disease and ulcerative colitis. Extracolonic manifestations are often associated with inflammatory bowel disease (ibd) and involve the liver, joints and skin. (12 Dec 1998) |
| injuries, poisonings, and occupational diseases | Disorders representing collectively the results of assault by external forces, rather than by organic or physiologic dysfunction or by pathogens. (12 Dec 1998) |
| intestinal diseases, parasitic | Infections of the intestines with a parasite. They are caused most commonly by intestinal nematodes (roundworms) and cestodes (tapeworms). (12 Dec 1998) |
| iris diseases | Diseases, dysfunctions, or disorders of or located in the iris. (12 Dec 1998) |
| obesity-related diseases | Obesity increases the risk of developing a number of diseases including: type 2 (adult-onset) diabetes high blood pressure (hypertension) stroke (cerebrovascular accident or cva) heart attack (myocardial infarction or mi) heart failure (congestive heart failure) cancer (only certain forms such as prostate and colon cancer) gallstones and gall bladder disease (cholecystitis) gout and gouty arthritis osteoarthritis (degenerative arthritis) of the knees, hips, and the lower back sleep apnea (failure to breath normally during sleep, lowering blood oxygen) pickwickian syndrome (obesity, red face, underventilation, and drowsiness). (12 Dec 1998) |
| occupational diseases | Diseases due to factors involved in one's employment. (12 Dec 1998) |
| optic nerve diseases | Diseases of the optic nerve. (12 Dec 1998) |
| orbital diseases | Diseases of the bony orbit and contents except the eyeball. (12 Dec 1998) |