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methylprednisolone hemisuccinate <chemical> (6 alpha,11 beta)-21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione. A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Pharmacological action: steroidal anti-inflammatory agents, antineoplastic agent, hormonal, glucocorticoids, synthetic, glucocorticoids, topical, neuroprotective agents.
Chemical name: Pregna-1,4-diene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-, (6alpha,11beta)-
(12 Dec 1998)
methylrosaniline chloride Hexamethylpararosanilin chloride;a compound that has been used in the external treatment of burns, wounds, and fungal infections of skin and mucous membranes, and internally for pinworm and certain fluke infections; used also as a stain for chromatin, amyloid, platelets in blood, fibrin, and neuroglia, and to differentiate among bacteria.
Synonym: methylrosaniline chloride.
(05 Mar 2000)
methyltestosterone <chemical> 17 beta-hydroxy-17-methylandrost-4-en-3-one.
Pharmacological action: anabolic steroids, androgens, synthetic, antineoplastic agent, hormonal.
Chemical name: Androst-4-en-3-one, 17-hydroxy-17-methyl-, (17beta)-
(12 Dec 1998)
methylthioadenosine Adenosine carrying an -SCH3 group in place of OH at position 5'; the -SCH3 group is transferred to alpha-aminobutyric acid to form l-methionine in some bacteria. Methylthioadenosine is formed from S-adenosyl-l-methionine in the course of spermidine synthesis by loss of the alanine moiety.
Synonym: thiomethyladenosine.
(05 Mar 2000)
methylthioinosine <chemical> 6-(methylthio)-9-beta-d-ribofuranosylpurine. An analog of inosine with a methylthio group replacing the hydroxyl group in the 6-position.
Chemical name: Inosine, 6-S-methyl-6-thio-
(12 Dec 1998)
methylthiolase <enzyme> Catalyses the cleavage of the methylthio group from 5-methylthioribose-1-phosphate
Chemical name: 5-methylthioribose-1-phosphate methylthiolase
Registry number: EC 3.3.1.-
(26 Jun 1999)
methylthiouracil <chemical> A thiourea antithyroid agent that inhibits the synthesis of thyroid hormone. It is used in the treatment of hyperthyroidism.
Pharmacological action: antithyroid agents.
Chemical name: 4(1H)-Pyrimidinone, 2,3-dihydro-6-methyl-2-thioxo-
(12 Dec 1998)
methyltocol A methylated tocol; e.g., tocotrienol, the tocopherols.
(05 Mar 2000)
methyltransferase <enzyme> That transfers a methyl group from S adenosyl methionine to a substrate. most commonly encountered in bacterial chemotaxis where the methyl accepting chemotaxis proteins (MCPs) become methylated in the course of adaptation.
(18 Nov 1997)
methyltransferases <enzyme> A subclass of enzymes of the transferase class that catalyze the transfer of a methyl group from one compound to another.
Registry number: EC 2.1.1.
(12 Dec 1998)
methyltyrosines A group of compounds that are methyl derivatives of the amino acid tyrosine.
(12 Dec 1998)
methylumbelliferone sulfatase <enzyme> Used as test substrate for arylsulfatases
Registry number: EC 3.1.6.-
Synonym: 4-methylumbelliferone sulfate sulfatase
(26 Jun 1999)
methylurea compounds Urea compounds which are substituted with one or more methyl groups.
(12 Dec 1998)
methylxanthines A chemical group of drugs derived from xanthine (a purine derivative); members of the group include theophylline, caffeine, and theobromine.
(05 Mar 2000)
methyprylone 3,3-Diethyl-2,4-dioxo-5-methylpiperidine;a sedative and hypnotic.
(05 Mar 2000)
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