| ectoprotein kinase | <enzyme> From outer plasma membranes; active site and substrate oriented extracellularly Registry number: EC 2.7.1.- Synonym: ecto-protein kinase, ectokinase (26 Jun 1999) |
|---|---|
| TIE-2 receptor tyrosine kinase | <enzyme> Expressed in developing vascular endothelial cells; unlike tie-1, also expressed in lens epithelium and heart epicardium; has the same organization of amino acid sequence motifs characteristic of tie-1; aa sequence of the intracellular and extracellular regions of tie-1 and tie-2 are 79% and 32% identical, respectively; aa sequence of both kinases given in first source Registry number: EC 2.7.10.- Synonym: tie-2-rtk (26 Jun 1999) |
| tie receptor tyrosine kinase | <enzyme> From human leukaemia cells; expressed in developing vascular endothelial cell; has homology with egf, bfgf, csf-1, pdgf and stem cell factor receptors; ligand and biologic function not known as of 12/92; tie-1 receptor tyrosine kinase is rat homolog of tie receptor tyrosine kinase; aa sequence known Registry number: EC 2.7.10.- Synonym: tie-1 receptor tyrosine kinase, tie-1 rtk (26 Jun 1999) |
| eif-2 kinase | <enzyme> A dsrna-activated camp-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsrna and ATP, eif-2 kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyses the phosphorylation of the alpha subunit of eif-2, leading to the inhibition of protein synthesis. Registry number: EC 2.7.10.- (12 Dec 1998) |
| TNF-IL1-activated protein kinase | <enzyme> Phosphorylates beta casein in vitro; not the same as casein kinase 1 and casein kinase 2; not activated by mitogens, celllular stresses or any other cytokines than il1 and tnf Registry number: EC 2.7.1.- Synonym: tip kinase, beta casein kinase (26 Jun 1999) |
| emb protein-tyrosine kinase | <enzyme> Isolated from murine mast cells Registry number: EC 2.7.1- Synonym: emb ptk (26 Jun 1999) |
| emt protein-tyrosine kinase | <enzyme> Isolated from murine mast cells Registry number: EC 2.7.1.- Synonym: emt ptk, itk protein, itk gene product, tsk protein, inducible t cell kinase (26 Jun 1999) |
| epidermal growth factor receptor protein-tyrosine kinase | <enzyme> The catalytic protein-tyrosine kinase domain found on the cytoplasmic beta-portion of epidermal growth factor receptor. Registry number: EC 2.7.1.- (12 Dec 1998) |
| tropomyosin kinase | <enzyme> From chick embryo; requires mg; ca and cyclic AMP not needed Registry number: EC 2.7.1.132 (26 Jun 1999) |
| TTK kinase | <enzyme> Can phosphorylate serine, threonine and tyrosine hydroxyamino acids and is associated with cell proliferation; amino acid sequence given in first source Registry number: EC 2.7.10.- (26 Jun 1999) |
| estradiol receptor tyrosine kinase | <enzyme> Calcium and calmodulin dependent Registry number: EC 2.7.1.- Synonym: ertk (26 Jun 1999) |
| JNK-activating protein kinase | <enzyme> A dual specificity kinase that activates jun kinases and p38-mpk2; amino acid sequence given in first source Registry number: EC 2.7.1.- Synonym: jnk kinase, jnkk, hemipterous protein, hep protein, jun amino-terminal kinase kinase, jn kinase kinase, hep gene product (26 Jun 1999) |
| tyrosine kinase | <enzyme> Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand binding domain, a single transmembrane domain and an intracellular tyrosine kinase domain and nonreceptor tyrosine kinases, which are soluble, cytoplasmic kinases. (18 Nov 1997) |
| tyrosyl tRNA synthetase kinase | <enzyme> From postribosomal supernatants of bom:nmri mouse liver; comigrates with tyrosyl trna synthetase during several purification steps Registry number: EC 2.7.1.- Synonym: tyr trna synthetase kinase (26 Jun 1999) |
| kanamycin kinase | <enzyme> A class of enzymes that inactivate aminoglycoside-aminocyclitol antibiotics by regiospecific phosphorylation of the 3' and/or 5' hydroxyl. Chemical name: ATP:kanamycin 3'-O-phosphotransferase Registry number: EC 2.7.1.95 (12 Dec 1998) |