| epilepsy | <disease, neurology> The paroxysmal transient disturbances of brain function that may be manifested as episodic impairment or loss of consciousness, abnormal motor phenomena, psychic or sensory disturbances or perturbation of the autonomic nervous system. Symptoms are due to paroxysmal disturbance of the electrical activity of the brain. On the basis of origin, epilepsy is idiopathic (cryptogenic, essential, genetic) or symptomatic (acquired, organic). On the basis of clinical and electroencephalographic phenomenon, four subdivisions are recognised: 1. Grand mal epilepsy (major epilepsy, haut mal epilepsy) subgroups: generalised, focal (localised), jacksonian (rolandic) 2. Petit mal epilepsy 3. Psychomotor epilepsy (temporal lobe epilepsy, psychic, psychic equivalent or variant) subgroups: psychomotor proper (tonic with adversive or torsion movements or masticatory phenomena), automatic (with amnesia) and sensory (hallucinations or dream states or d굁. Vu) 4. Autonomic epilepsy (diencephalic), with flushing, pallor, tachycardia, hypertension, perspiration or other visceral symptoms. Synonym: epilepsia. Origin: Gr. Epilepsia = seizure (14 May 1997) |
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| epilepsy with grand mal seizures on awakening | Generalised epilepsy syndrome characterised by onset in the second decade of life, typically with generalised tonic-clonic seizures, of which most occur shortly after awakening (regardless of the time of day) and are exacerbated by sleep deprivation. There is a genetic predisposition and EEG shows one of several generalised patterns of interictal discharges; photosensitivity is common. (05 Mar 2000) |
| epilepsy with myoclonic absences | A form of generalised epilepsy characterised by absence seizures, severe bilateral rhythmic clonic jerks often associated with tonic contraction, and an EEG 3 Hz spike and wave pattern. Age of onset is usually around seven years and males are more often affected. (05 Mar 2000) |
| epilepsy, absence | Epileptic seizures that consist of a sudden cessation of ongoing conscious activity without convulsive muscular activity or loss of postural control. These seizures may be so brief as to be inapparent, lasting seconds and occasionally several minutes. Absence seizures usually begin in otherwise neurologically normal children and rarely appear for the first time in adults. The seizures may occur hundreds of times per day and go on for weeks or months before it is recognised that a child is having seizures. (12 Dec 1998) |
| epilepsy, complex partial | Epileptic seizures that are episodic changes in behaviour in which an individual loses conscious contact with the environment. The onset of such seizures involves any of a variety of auras: deja-vu, an unusual smell, a sudden intense emotional feeling, a sensory illusion such as micropsia (objects growing smaller) or macropsia (objects growing larger), or other sensory hallucination. There may be a cessation of activity with some minor motor activity such as lip smacking, walking aimlessly, or other automatisms. The seizures may also be accompanied by the unconscious performance of highly skilled activities such as driving a car. When the seizure ends, the individual is amnesic for events that took place during the seizure and may take minutes or hours to recover fully to consciousness. (12 Dec 1998) |
| epilepsy, frontal lobe | Epileptic seizures arising from the frontal lobe characterised by simple partial, complex partial, secondary generalised seizures, or combinations of these. The seizures, which are short in duration, may occur several times a day, mostly during sleep. Affected individuals usually have prominent motor manifestations which are tonic or postural, complex gestational automatisms at the onset, and fall to the ground when the discharge is bilateral. Status epilepticus is a frequent complication. (12 Dec 1998) |
| epilepsy, generalised | Epileptic seizures in which the first clinical changes indicate initial involvement of both hemispheres of the brain, as opposed to epileptic seizures involving a particular focal point of the brain (epilepsy, partial). Generalised seizures can be convulsive or non-convulsive. Consciousness may be impaired and this impairment may be the initial manifestation of the seizure. Motor manifestations, if present, are also bilateral. (12 Dec 1998) |
| epilepsy, myoclonic | A progressive encephalopathy characterised by myoclonic jerks (single or repetitive muscle contractions involving one body part or the entire body), mental retardation, and ataxia. The disease, an autosomal recessive form of epilepsy, occurs usually at puberty. The most significant pathological findings are lafora's inclusion bodies, which contain mucopolysaccharides. (12 Dec 1998) |
| epilepsy, partial | Epileptic seizures that originate at a specific location or focal point in the cortex of the brain and either remain localised or may generalise. These seizures occur without the loss of consciousness of the individual. The specific clinical symptoms depend on the area of the cortex involved. (12 Dec 1998) |
| epilepsy, posttraumatic | Epileptic seizures occurring as the result of trauma such as a gunshot wound or other injury to the brain. (12 Dec 1998) |
| epilepsy, rolandic | A benign, autosomal, dominant form of epilepsy occurring in children characterised clinically by arrest of speech, by muscular contractions of the side of the face and arm and electroencephalographically by high voltage spikes followed by slow waves in the rolandic area leads. Named for luigi rolando, an italian anatomist (1773-1831). (12 Dec 1998) |
| epilepsy, temporal lobe | Epileptic seizures characterised by simple partial seizures, complex partial seizures, and secondary generalised seizures, or combinations of these. Seizures may present with autonomic and/or psychic symptoms and certain sensory phenomena such as olfactory and auditory. most common is an epigastric rising sensation. Some seizures may begin with motor arrest and continue with oro-alimentary automatisms (with other automatisms following). Attacks are followed by amnesia and recovery is gradual. Usually, there is a history of febrile seizures in the individual or a history of seizures in the family. Seizures occur in clusters, randomly, or at intervals. (12 Dec 1998) |
| epilepsy, tonic-clonic | Primary generalised epileptic seizures, starting without warning, characterised by loss of consciousness, tonic contraction of muscles, loss of postural control, and production of a cry by the forced expiration of air due to contraction of the respiratory muscles. The individual then falls to the floor and remains rigid for a few seconds, after which a series of rhythmic contractions occur in all four limbs. This clonic phase can last for a variable period, ending only upon muscle relaxation. Upon recovery, there is a gradual return to consciousness, disorientation, amnesia for the seizure, sometimes retrograde amnesia as well, headache, and drowsiness. The individual may not return to baseline functioning for days. (12 Dec 1998) |
| epileptic | 1. One affected with epilepsy. 2. A medicine for the cure of epilepsy. Source: Websters Dictionary (01 Mar 1998) |
| epileptic dementia | Dementia occurring in an individual afflicted with epilepsy, and thought to be a result of prolonged seizures, the epileptogenic brain lesion, or antiepileptic drugs. Hebephrenic dementia, dementia with hebephrenic symptoms. (05 Mar 2000) |
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