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calcified cartilage Cartilage in which calcium salts are deposited in the matrix; it occurs prior to replacement by osseous tissue and sometimes in aging cartilage.
(05 Mar 2000)
calcified liver metastases <radiology> Mucinous carcinoma of GI tract (colon, rectum, stomach), endocrine pancreatic carcinoma, leiomyosarcoma, osteosarcoma, malignant melanoma, papillary serous ovarian cystadenocarcinoma, lymphoma, pleural mesothelioma, neuroblastoma, breast carcinoma, medullary thyroid carcinoma, renal cell carcinoma, lung carcinoma, testicular carcinoma see: liver metastases
(12 Dec 1998)
calcify To deposit or lay down calcium salts, as in the formation of bone.
(05 Mar 2000)
calcifying and keratinizing odontogenic cyst A mixed radiolucent-radiopaque lesion of the jaws with features of both a cyst and a solid neoplasm; characterised microscopically by an epithelial lining showing a palisaded layer of columnar basal cells, presence of ghost cell keratinization, dentinoid, and calcification.
Synonym: calcifying and keratinizing odontogenic cyst, Gorlin cyst.
(05 Mar 2000)
calcifying epithelial odontogenic tumour A benign epithelial odontogenic neoplasm derived from the stratum intermedium of the enamel organ; a painless, slowly growing, mixed radiolucent-radiopaque lesion characterised histologically by cords of polyhedral epithelial cells, deposits of amyloid, and spherical calcifications.
Synonym: Pindborg tumour.
(05 Mar 2000)
calcifying odontogenic cyst A mixed radiolucent-radiopaque lesion of the jaws with features of both a cyst and a solid neoplasm; characterised microscopically by an epithelial lining showing a palisaded layer of columnar basal cells, presence of ghost cell keratinization, dentinoid, and calcification.
Synonym: calcifying and keratinizing odontogenic cyst, Gorlin cyst.
(05 Mar 2000)
calcigerous Producing or carrying calcium salts.
Origin: calcium + L. Gero, to bear
(05 Mar 2000)
calcimedins annexins, haem
(18 Nov 1997)
calcimycin <chemical> An ionophorous, polyether antibiotic from streptomyces chartreusensis. It binds and transports cations across membranes and uncouples oxidative phosphorylation while inhibiting atpase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.
Pharmacological action: antibiotics, ionophores.
Chemical name: 4-Benzoxazolecarboxylic acid, 5-(methylamino)-2-((3,9,11-trimethyl-8-(1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-, (6S-(6alpha(2S*,3S*),8beta(R*),9beta,11alpha))-
(12 Dec 1998)
calcination <chemistry> The process of heating a solid below its melting point to break it down into another compound (for instance, heating calcium carbonate to send off carbon dioxide gas and create calcium oxide).
(21 Mar 1998)
calcine To expel water and volatile matter by heat.
(05 Mar 2000)
calcined magnesia <chemical> Magnesium oxide (mgo). An inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.
Pharmacological action: antacids, cathartic.
Chemical name: Magnesium oxide (MgO)
(12 Dec 1998)
calcineurin <protein> Calmodulin stimulated protein phosphatase (EC 3.1.3.16), the major calmodulin binding protein in brain.
Enzymic activity is inhibited by binding of immunophilin ligand complex (immunophilin alone does not bind) and therefore may play a part in the mechanism of action of cyclosporin A and FK506. Thought also to be involved in the control of sperm motility.
(21 Mar 1998)
calcinosis <dermatology> A condition which is characterised by the deposition of calcium in nodular foci in the body tissues.
(21 Mar 1998)
calcinosis circumscripta Localised deposits of calcium salts in the skin and subcutaneous tissues, usually surrounded by a zone of granulomatous inflammation; clinically, the lesions resemble the tophi of gout.
(05 Mar 2000)
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