| herpes virus 3, human | The type species of varicellovirus causing chickenpox (varicella) and herpes zoster (shingles) in humans. (12 Dec 1998) |
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| herpes virus 4, human | A species of lymphocryptovirus cultivated from cultures of burkitt lymphoma. It is thought to be the causative agent of infectious mononucleosis. (12 Dec 1998) |
| herpes virus 6, human | The type species of roseolovirus isolated from patients with aids and other lymphoproliferative disorders. It infects and replicates in fresh and established lines of haematopoietic cells and cells of neural origin. It also appears to alter nk cell activity. Hhv-6 (hblv) antibodies are elevated in patients with aids, sjogren's syndrome, sarcoidosis, chronic fatigue syndrome, and certain malignancies. Hhv-6 is the cause of exanthema subitum and has been implicated in encephalitis. (12 Dec 1998) |
| herpes virus 7, human | A species of the family herpesviridae isolated from activated, CD4-positive T-lymphocytes taken from the blood of a healthy human. (12 Dec 1998) |
| prothrombin deficiency | A congenital or acquired disorder of blood clotting where there is a deficiency of factor II (prothrombin), one of 20 necessary plasma proteins for normal blood coagulation. Acquired factor II deficiency may result from vitamin K deficiency, severe liver disease and anticoagulant drugs. Symptoms include abnormal bleeding, nosebleeds, abnormal menstrual bleeding, easy bruising and umbilical cord bleeding at birth. Treatment involves the infusion of fresh frozen plasma. Vitamin K may be administered in select cases. (27 Sep 1997) |
| proximal femoral focal deficiency | A congenital defect in which variable portions of the upper end of the femur are reduced or absent. (05 Mar 2000) |
| pseudocholinesterase deficiency | An autosomal dominant disorder manifested by exaggerated responses to drugs ordinarily hydrolyzed by serum pseudocholinesterase (e.g., succinylcholine); believed to entail production of a variant enzyme that is less active than the normal enzyme in hydrolyzing appropriate substrates, but also abnormally resistant to the effects of anticholinesterases. (05 Mar 2000) |
| secondary antibody deficiency | Immunodeficiency in which there is no evident defect in the lymphoid tissues, but rather hypercatabolism or loss of immunoglobulins such as occurs in familial idiopathic hypercatabolic hypoproteinaemia or in defects associated with the nephrotic syndrome. Synonym: secondary agammaglobulinaemia, secondary antibody deficiency, secondary hypogammaglobulinaemia. (05 Mar 2000) |
| selective immunoglobulin A deficiency | <immunology> An inherited disorder in which there is a markedly reduced or absent IgA, resulting in immature IgA-bearing B-cells. (05 Mar 2000) |
| selenium deficiency | deficiency of the essential mineral selenium causes keshan disease, a fatal form of cardiomyopathy (disease of the heart muscle) first observed in keshan province in china and since found elsewhere. According to the national academy of sciences, the recommended dietary allowances of selenium are 70 milligrams per day for men and 55 milligrams per day for women. Food sources of selenium include seafoods, some meats such as kidney and liver, and some grains and seeds (12 Dec 1998) |
| human | Belonging to man or mankind; having the qualities or attributes of a man; of or pertaining to man or to the race of man; as, a human voice; human shape; human nature; human sacrifices. "To err is human; to forgive, divine." (Pope) Origin: L. Humanus; akin to homo man: cf. F. Humain. See Homage, and cf. Humane, Omber. Source: Websters Dictionary (01 Mar 1998) |
| human a1-proteinase inhibitor | A glycoprotein that is the major protease inhibitor of human serum, is synthesised in the liver, and is genetically polymorphic due to the presence of over 20 alleles; individuals appropriately homozygous are deficient in a1-trypsin and are predisposed to pulmonary emphysema and juvenile hepatic cirrhosis because of alterations in the amino acid and sialic acid components of the glycoprotein. A1-Antitrypsin also inhibits thrombin. Synonym: a1-trypsin inhibitor, human a1-proteinase inhibitor. (05 Mar 2000) |
| human activities | Activities performed by humans. (12 Dec 1998) |
| human antihemophilic factor | A lyophilised concentrate of factor VIII, obtained from fresh normal human plasma; used as a haemostatic agent in haemophilia. Synonym: antihemophilic globulin, human antihemophilic fraction. (05 Mar 2000) |
| human antihemophilic fraction | A lyophilised concentrate of factor VIII, obtained from fresh normal human plasma; used as a haemostatic agent in haemophilia. Synonym: antihemophilic globulin, human antihemophilic fraction. (05 Mar 2000) |