| Levaditi stain | <technique> A silver nitrate stain for blackening spirochetes in tissue sections. (05 Mar 2000) |
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| Lillie's allochrome connective tissue stain | <technique> A procedure using PAS, haematoxylin, picric acid, and methyl blue; used for distinction between basement membrane and reticulin, and for demonstration of arteriosclerotic lesions. (05 Mar 2000) |
| Lillie's azure-eosin stain | <technique> A stain in which an azure eosinate solution is used to stain bacteria and rickettsiae in tissues. (05 Mar 2000) |
| Lillie's ferrous iron stain | <technique> A method using potassium ferrocyanide in acetic acid which demonstrates melanins as a deep green colour; lipofuscins and haem pigments are unreactive. (05 Mar 2000) |
| Lillie's sulfuric acid Nile blue stain | <technique> A technique for showing fatty acids when present in high concentrations. (05 Mar 2000) |
| Lison-Dunn stain | <technique> A technique using leuco patent blue V and hydrogen peroxidase to demonstrate haemoglobin peroxidase on time sections and smears. (05 Mar 2000) |
| Loeffler's caustic stain | <technique> A stain for flagella, utilizing an aqueous solution of tannin and ferrous sulfate with the addition of an alcoholic fuchsin stain. (05 Mar 2000) |
| Loeffler's stain | <technique> A stain for flagella; the specimen is treated with a mixture of ferrous sulfate, tannic acid, and alcoholic fuchsin, then stained with aniline-water fuchsin or gentian violet made alkaline with sodium hydroxide solution. (05 Mar 2000) |
| Luna-Ishak stain | <technique> A staining method using celestine blue and acid fuchsin in which bile canaliculi stain pink to red. (05 Mar 2000) |
| acetoacetyl-acyl carrier protein synthase | <enzyme> E coli enzyme, that catalyses condensation of malonyl-acyl carrier protein plus acetyl-acyl carrier protein; not inhibited by cerulenin Registry number: EC 2.3.1.- Synonym: acetoacetyl-acp synthase (26 Jun 1999) |
| acid soluble spore protein | <molecular biology> A DNA binding protein in the spores of some bacteria, thought to stabilise the DNA in an A configuration, so protecting it from cleavage by enzymes or UV light. (18 Nov 1997) |
| acute-phase protein | <haematology> These plasma proteins (in addition to fibrinogen) increase 25% or more in response to inflammation and injury are under direct control of interleukin-6 (IL-6) (hepatocyte-stimulating factor). Other proteins which increase are ceruloplasmin, C3 and C4 which increase 50% or more; alpha-1 acid glycoprotein, alpha-1 antitrypsin, haptoglobin and fibrinogen (the major determinant of viscosity 1 ) which increase two- to fourfold; C-reactive protein (CRP) and serum amyloid A which increase several hundred-fold. Despite long-held clinical opinion to the contrary, available data indicate that neither ESR nor measurement of specific acute-phase reactants are useful in excluding underlying infection or inflammation regardless of the pretest probability. These proteins are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. They can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumour markers. See also: amyloid, c-reactive protein, erythrocyte sedimentation rate, viscosity. (25 Jun 1999) |
| acyl-(acyl-carrier-protein)-phospholipid acyltransferase | <enzyme> Catalyses the formation of phosphatidylethanolamine from acyl-acyl carrier protein and 2-acyl-sn-glycero-3-phosphoethanolamine Registry number: EC 2.3.1.40 Synonym: 2-acyl-gpe acyltransferase, 2-acylglycerophosphoethanolamine acyltransferase (26 Jun 1999) |
| acyl-(acyl-carrier-protein)-UDP-N-acetylglucosamine acyltransferase | <enzyme> E coli enzyme involved in lipid a biosynthesis; uses beta-hydroxymyristoyl-acyl carrier protein to form udp-3-monoacyl-n-acetylglucosamine; amino acid sequence given in second source Registry number: EC 2.3.1.129 Synonym: udp-aguatransferase, lpxa protein, udp-n-acetylglucosamine-3-acyltransferase, udp-n-acetylglucosamine 3-o-acyltransferase, udp-3-o-(r-3-hydroxymyristoyl)glucosamine-n-acyltransferase, lpxd protein, fira gene product, fira protein (26 Jun 1999) |
| acyl carrier protein | <protein> A small (77 peptides long) protein which binds six other enzymes involved in fatty acid synthesis. It was first isolated in E. Coli bacteria. (09 Oct 1997) |
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