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massive c. coagulation of the spinal fluid so as to form an almost solid clot; a condition seen in some cases of Froin's syndrome in meningomyelitis or tumor of the cord.
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massive h. loss of blood so rapid and profuse that shock supervenes unless appropriate replacement is instituted promptly.
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massive hepatic n. massive necrosis of the liver, a rare complication of viral hepatitis (fulminant hepatitis) that may also result from exposure to hepatotoxins or from drug hypersensitivity. A lobe or the entire liver shrinks, becoming a soft, flabby, yellow-brown to green mass with a wrinkled capsule; there is confluent necrosis of hepatocytes, often with fatty change. Mortality is 60 to 90 per cent. Formerly called acute parenchymatous hepatitis and acute yellow atrophy.
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massive s. a spasm characterized by contraction of most of the body musculature. Cf. seizure and infantile massive s.
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Masson s. a trichrome stain for connective tissue.
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