| glutathione synthetase | <enzyme> An enzyme that catalyses the formation of glutathione, ADP, and orthophosphate from gamma-glutamylcysteine, ATP, and glycine; a deficiency will lead to metabolic acidosis and progressive brain dysfunction. (05 Mar 2000) |
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| glutathione synthetase deficiency | An inborn error of metabolism associated with massive urinary excretion of 5-oxyproline, elevated levels of 5-oxyproline in the blood and cerebrospinal fluid, severe metabolic acidosis, tendency toward haemolysis, and defective central nervous systems function. Glutathione synthetase deficiency has been reported as a generalised condition or with a deficiency restricted to erythrocytes. (05 Mar 2000) |
| glutathionylspermidine synthetase | <enzyme> From crithidia fasciculata; catalyses the synthesis of n(1)-and n(8)-glutathionylspermidine from ATP/mg, glutathione and spermidine; mw 90 kD; different from trypanothione synthetase Registry number: EC 6.3.1.- Synonym: gsh-sp synthetase (26 Jun 1999) |
| glycerophosphorylcholine synthetase | <enzyme> Forms sn-glycerol-3-phosphorylcholine from cdpcholine and glycerol-3-phosphate Registry number: EC 2.6.99.- Synonym: cdp-choline-3-glycerophosphate cholinetransferase, cdp-gpccholinetransferase (26 Jun 1999) |
| glycogen synthetase | <enzyme> An enzyme which makes amylose out of glucose molecules (a type of sugar) and attaches them to glycogen (a type of polysaccharide). (09 Oct 1997) |
| glyoxylate synthetase | <enzyme> Catalyses the condensation of two formate molecules into glyoxylate; a tetramer with mw of 160 kD with a subunit mw of 40 kD; isolated from green potato-tuber chloroplasts Registry number: EC 4.1.3.- (26 Jun 1999) |
| GMP synthetase | <enzyme> Consider also GMP synthetase (glutamine hydrolysing) EC 6.3.5.2 Registry number: EC 6.3.4.1 (26 Jun 1999) |
| peptide synthetase | Any enzyme that catalyses the synthesis of peptide bonds, with the hydrolysis of a nucleoside triphosphate. (05 Mar 2000) |
| peptidoglycan synthetase | <chemical> Contains peptidoglycan transglycosylase and peptidoglycan transpeptidase; see also record for penicillin-binding protein; until 3/5/84 pbp 1a, 2, 3 were synonyms to penicillin-binding protein; pbpc encodes penicillin-binding protein 3 Chemical name: synthetase, peptidoglycan Synonym: pbp-1b, penicillin binding protein 1bs, penicillin-binding protein 1a, penicillin-binding protein 1b, penicillin-binding protein 2, penicillin-binding protein 3, penicillin-binding protein 1b gamma, pbp1a gene product, pona gene product, ftsi gene product, pbpc gene product, pbp3x protein (26 Jun 1999) |
| peptolide SDZ 214-103 synthetase | <chemical> Catalyses at least 39 partial reaction steps in the synthesis of sdz 214-103 by the fungus cylindrotrichum oligospermum Chemical name: synthetase, peptolide Synonym: sdz 214-103 synthetase (26 Jun 1999) |
| chlorophyll synthetase | <enzyme> Incorporates geranylgeraniol into chlorophyll; requires ATP; as of 11/80 not clear whether this is a synthetase or a combination of a kinase and a transferase Registry number: EC 6.1.- (26 Jun 1999) |
| cholesteryl ester synthetase | <enzyme> Independent of coenzyme a; dependent on bile salts Registry number: EC 2.3.1.- (26 Jun 1999) |
| guanosine pentaphosphate synthetase | <enzyme> Also possesses polynucleotide phosphorylase activity; genbank u19858 Registry number: EC 2.7.6.- Synonym: guanosine pentaphosphate synthetase I, gpsi enzyme (26 Jun 1999) |
| cholyl-coenzyme A synthetase | cholate ligase |
| phosphoribosylformylglycinamidine synthetase | <enzyme> Involved in purine nucleotide biosynthesis; fgam synthase I contains the glutamine amide transfer domain and fgam synthase II contains the aminator domain of fgam synthase Chemical name: 2-formamido-n-ribosylacetamide 5'-phosphate l-glutamine amido-ligase (adenosine diphosphate) Registry number: EC 6.3.5.3 Synonym: formylglycineamide ribonucleotide amidotransferase, fgar amidotransferase, fgam synthetase, fgar synthetase, fgam synthase, fgam synthase I, fgam synthase II, 5'-phosphoribosyl-n-formylglycinamide amidotransferase (26 Jun 1999) |