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relapse the return of a disease after its apparent cessation. Cf. recrudescence.
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relapsing a. recurrence of appendiceal inflammation after improvement; recurrent appendicitis.
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relapsing f. an acute infectious, systemic, usually self-limited disease of worldwide distribution, caused by various species of the genus Borrelia; it may be either endemic or epidemic and is transmitted by the bites of either the body louse (Pediculus humanus corporis), for which humans are the reservoir, or Ornithodoros ticks, for which rodents and other animals are reservoirs. Characteristics include alternating periods with and without fever and spirochetemia, each lasting for several days. During the febrile periods symptoms include chills, headache, fatigue, myalgia, arthralgia, anorexia, cough, abdominal pain, and sometimes coagulation disturbance, hepatosplenomegaly, psychic disturbances, petechial rash, and vomiting; treatment may be complicated by severe Jarisch-Herxheimer reaction. Both epidemiological forms of the disease are known by various descriptive and local names, including recurrent, or spirillum f.
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relapsing febrile nodular nonsuppurative p. a form characterized by recurrent episodes of fever with crops of single or multiple, erythematous, tender or painless subcutaneous nodules on the lower limbs and trunk, which resolve and usually leave a depression in the skin. It is most often seen in women and may occur alone or associated with other disorders. Called also Christian-Weber disease, nodular nonsuppurative p., and Weber-Christian p., disease, or syndrome.
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relapsing p. a disease of unknown etiology with a chronic course and sometimes recurrence, marked by inflammatory and degenerative lesions of cartilage in the joints, ears, nose, trachea, bronchi, and elsewhere, with deformities such as floppy ear and saddle nose; if the tracheal or bronchial wall collapses, respiratory obstruction may occur. The aorta, sclera, and cornea are also affected. Called also chronic atrophic p., p. chronica atrophicans, and polychondropathia.
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