| choline dihydrogen citrate | <chemical> A lipotropic agent. Chemical name: (2-hydroxyethyl)trimethylammonium citrate. (17 Jul 2002) |
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| choline esterase I | <enzyme, neurology, physiology> An enzyme that breaks down unused acetylcholine in the synaptic cleft (the space between neurons), this enzyme is necessary to restore the synaptic cleft so it is ready to transmit the next nerve impulse. (06 May 1997) |
| choline esterase II | <enzyme> An enzyme that breaks down acetylcholine tostop its action. (22 May 1997) |
| choline kinase | <enzyme> An enzyme that is active in the first step of choline phosphoglyceride (lecithin) biosynthesis by catalyzing the phosphorylation of choline to phosphorylcholine in the presence of ATP. Ethanolamine and its methyl and ethyl derivatives can also act as acceptors. Chemical name: ATP:choline phosphotransferase Registry number: EC 2.7.1.32 (12 Dec 1998) |
| choline monooxygenase | <enzyme> Catalyses conversion of choline to the hydrate form of betaine aldehyde. Registry number: EC 1.- Synonym: cmo enzyme (26 Jun 1999) |
| choline o-acetyltransferase | <enzyme> An enzyme that catalyses the formation of acetylcholine from acetyl-CoA and choline. Chemical name: Acetyl-CoA:choline O-acetyltransferase Registry number: EC 2.3.1.6 (12 Dec 1998) |
| choline phosphatase | <enzyme> An enzyme found mostly in plant tissue. It hydrolyzes glycerophosphatidates with the formation of a phosphatidic acid and a nitrogenous base such as choline. This enzyme also catalyses transphosphatidylation reactions. Chemical name: Phosphatidylcholine phosphatidohydrolase Registry number: EC 3.1.4.4 (12 Dec 1998) |
| choline phosphokinase | <enzyme> An enzyme that is active in the first step of choline phosphoglyceride (lecithin) biosynthesis by catalyzing the phosphorylation of choline to phosphorylcholine in the presence of ATP. Ethanolamine and its methyl and ethyl derivatives can also act as acceptors. Chemical name: ATP:choline phosphotransferase Registry number: EC 2.7.1.32 (12 Dec 1998) |
| choline salicylate | Choline salt of salicyclic acid, an analgesic and antipyretic (because of the salicylate moiety). (05 Mar 2000) |
| choline theophyllinate | A true salt of theophylline; it has mild diuretic, myocardial stimulating vasodilator, and bronchodilator actions, with the same uses as theophylline, but is better absorbed and less irritating. Synonym: choline theophyllinate. (05 Mar 2000) |
| choline-phosphate cytidylyltransferase | <enzyme> An enzyme that catalyses the transfer of cytidylate (CMP) to choline phosphate to form CDPcholine. It is the rate-limiting enzyme in the choline pathway for the biosynthesis of phosphatidylcholine. Its activity is increased by glucocorticoids. Registry number: EC 2.7.7.15 (12 Dec 1998) |
| cholinephosphotransferase | <enzyme> An enzyme catalyzing the reaction between CDP-choline and 1,2-diacylglycerol to form a phosphatidylcholine and CMP. The last step in lecithin biosynthesis. (05 Mar 2000) |
| cholinergic | <pharmacology> Resembling acetylcholine in pharmacological action, stimulated by or releasing acetylcholine or a related compound. (15 Jan 1998) |
| cholinergic agent | An agent that mimics the action of the parasympathetic nervous system (e.g., methacholine). (05 Mar 2000) |
| cholinergic agents | Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons. The term cholinergic agents is sometimes still used in the narrower sense of muscarinic agonist, although most modern texts discourage that usage. (12 Dec 1998) |