| ADC | adult day care [facility]; affective disorders clinic; Aid to [Families with] Dependent Children; AI... |
|---|---|
| Ag-Ab | antigen-antibody complex |
| ALC | absolute lymphocyte count; acute lethal catatonia; aided living center; Alternative Lifestyle Checkl... |
| ALS-PD | amyotrophic lateral sclerosis-parkinsonism-dementia [complex] |
| APCD | acquired prothrombin complex deficiency [syndrome]; adult polycystic kidney disease |
| calcium-binding protein | <biochemistry> There are two main groups of calcium binding proteins, those that are similar to calmodulin and are called EF hand proteins and those that bind calcium and phospholipid (e.g. Lipocortin) and that have been grouped under the generic name of annexins. Many other proteins will bind calcium, although the binding site usually has considerable homology with the calcium-binding domains of calmodulin. They can act as transport proteins, regulator proteins or activator proteins. There is also a vitamin D-dependent variant which is a protein that plays a fundamental role in the vitamin d mediated transport of calcium in reptiles, amphibians, birds and mammals. It is found in the intestine, kidneys, egg shell gland, brain, and possibly other organs. Its molecular weight is species dependent. (12 May 2002) |
|---|---|
| calcium-calmodulin dependent protein kinase | <enzyme> A calmodulin-dependent enzyme that catalyses the phosphorylation of proteins. This enzyme is also sometimes dependent on calcium. A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light chains, and the microtubule-associated proteins. Registry number: EC 2.7.10.- (12 Dec 1998) |
| calcium-dependent protein kinase | <enzyme> Mw 51,000; requires ca; not stimulated by calmodulin, phospholipids or diacylglycerol; phosphorylates casein and histones forming primarily phosphoserine and phosphothreonine, respectively Registry number: EC 2.7.1.- Synonym: paramecium ca-dependent protein kinase (26 Jun 1999) |
| calcium dependent regulator protein | <protein> (CDRP) Early name for calmodulin. (18 Nov 1997) |
| calmodulin-dependent protein kinase IV kinase | <enzyme> Phosphorylates and activates cam-kinase iv; from brain Registry number: EC 2.7.10.- Synonym: cam-kinase iv kinase (26 Jun 1999) |
| cAMP receptor protein | catabolite (gene) activator protein |
| cap binding protein | <molecular biology, protein> Protein (24 kD) with affinity for cap structure at 5' end of mRNA that probably assists, together with other initiation factors, in binding the mRNA to the 40S ribosomal subunit. Translation of mRNA in vitro is faster if it has a cap binding protein. (18 Nov 1997) |
| p150 protein kinase | <enzyme> Mw 150 kD; forms a cellular complex with phosphatidylinositol 3-kinase; a homolog of vps15 protein kinase; amino acid sequence given in first source Registry number: EC 2.7.1.- (26 Jun 1999) |
| p21(ras) farnesyl-protein transferase | <enzyme> Transfers the farnesyl moiety from farnesyl pyrophosphate to a cysteine in p21(ras) proteins; composed of an alpha and a beta subunit Registry number: EC 2.5.1.- Synonym: farnesyl-protein transferase p21(ras), ras p21 farnesyl-protein transferase, protein-cysteine farnesyltransferase, pc farnesyltransferase, protein farnesyltransferase, p21(ras) farnesyltransferase, farnesyl-protein transferase-alpha, farnesyl-protein transferase-beta, ft alpha, ft beta, caax farnesyltransferase, ftase enzyme (26 Jun 1999) |
| P400 protein | <protein> Inositol 1,4, 5 triphosphate receptor (InsP3 R). Key protein to understanding mechanisms of InsP3 mediated Ca mobilisation. Originally found as a cerebellar glycoprotein of 250 kD and subsequently shown to be identical to the InsP3 receptor protein. (18 Nov 1997) |
| p54 protein kinase | <enzyme> A stress-activated kinase related to erk-1 and erk-2 but activated preferentially by heat shock, protein-synthesis inhibitors and thf-alpha; phosphorylates c-jun proteins; genbank l27111 Registry number: EC 2.7.10.- Synonym: p54 map kinase (26 Jun 1999) |
| gag protein | <molecular biology> The protein of the nucleocapsid shell around the RNA of a retrovirus. (18 Nov 1997) |
| galactose binding protein | <protein> A bacterial periplasmic protein, most studied in E. Coli, that acts both as a sensory element in the detection of galactose as a chemotactic signal and in the uptake of the sugar. (18 Nov 1997) |
| macrophage inflammatory protein | <cytokine> A chemokine that is chemotactic for neutrophils and monocytes, stimulates macrophages, and may play a role in regulating haematopoiesis. Its two variants, mip-1alpha and mip-1beta, are 60% homologous to each other. They are heparin-binding proteins that exhibit a number of inflammatory and immunoregulatory activities. Originally identified as secretory products of macrophages, these chemokines are produced by a variety of cell types including neutrophils, fibroblasts, and epithelial cells. They most likely also play a significant role in respiratory tract defenses. (20 Sep 2002) |
| Varciella-Zoster ORF47-associated protein kinase | <enzyme> Catalyses the in vitro phosphorylation of the vzv orf62 protein Registry number: EC 2.7.1.- Synonym: vzv orf47-apk (26 Jun 1999) |