| IMMC | interdigestive migrating motor complex |
|---|---|
| ISCO | immunostimulating complex [vaccine] |
| IVJC | intervertebral joint complex |
| LHC | Langerhans cell histiocytosis; left heart catheterization; left hypochondrium; light-harvesting comp... |
| LMC | large motile cell; lateral motor column; left main coronary [artery]; left middle cerebral [artery];... |
| macrophage inflammatory protein | <cytokine> A chemokine that is chemotactic for neutrophils and monocytes, stimulates macrophages, and may play a role in regulating haematopoiesis. Its two variants, mip-1alpha and mip-1beta, are 60% homologous to each other. They are heparin-binding proteins that exhibit a number of inflammatory and immunoregulatory activities. Originally identified as secretory products of macrophages, these chemokines are produced by a variety of cell types including neutrophils, fibroblasts, and epithelial cells. They most likely also play a significant role in respiratory tract defenses. (20 Sep 2002) |
|---|---|
| Varciella-Zoster ORF47-associated protein kinase | <enzyme> Catalyses the in vitro phosphorylation of the vzv orf62 protein Registry number: EC 2.7.1.- Synonym: vzv orf47-apk (26 Jun 1999) |
| MAG protein | <protein> Myelin associated glycoprotein, one of the immunoglobulin superfamily. (18 Nov 1997) |
| palmitoyl-protein thioesterase | <enzyme> Cleaves palmitoyl-cysteine bond of proteins; genbank u44772; do not confuse with palmitoyl-acyl carrier protein thioesterase Registry number: EC 3.1.2.- Synonym: palmitoyl-ras thioesterase, protein palmitoyl thioesterase (26 Jun 1999) |
| major intrinsic protein | <protein> Family of structurally related proteins with 6 transmembrane segments, associated with gap junctions or vacuoles. MIP is found in lens fibre gap junctions. Other members: nodulin 26 (soybean), tonoplast intrinsic protein (TIP) found in plant storage vacuoles, Drosophila neurogenic protein big brain. (18 Nov 1997) |
| gap-43 protein | A nervous tissue specific protein which is highly expressed in neurons during development and nerve regeneration. It has been implicated in neurite outgrowth, long-term potentiation, signal transduction, and neurotransmitter release. It is also a substrate of protein kinase c. (12 Dec 1998) |
| GAP protein | <molecular biology> Originally purified as a 125 kD protein from bovine brain (1044 amino acids), stimulates the GTPase activity of ras p21 and thereby switches it to the inactive state. GAP may itself be regulated by phospholipids and by phosphorylation on a tyrosine residue by growth factor receptors (PDGF R, EGF R). The neurofibromatosis type 1 gene NF1) codes for a protein homologous to GAP. GAP has both SH2 and SH3 domains. Another example is sar 1 (from yeast). (18 Nov 1997) |
| MAK-L protein kinase | <enzyme> Putative protein serine threonine kinase from microtubules, nuclei and centromeres of cho-k1 cells; 72% identical to human kiaa0204 protein; genbank af002245 Registry number: EC 2.7.10.- Synonym: microtubule-associated kinase, large, 3d2 protein, cho-k1 (26 Jun 1999) |
| Mak protein kinase | <enzyme> A testis-specific kinase expressed in the meiotic phase of spermatogenesis in rat; one of the physiological substrates is a 210 kD phosphoprotein; distantly related to cdc2 kinase; has been sequenced Registry number: EC 2.7.10.- Synonym: mak gene product, male germ cell-associated kinase (26 Jun 1999) |
| malonyl-CoA-acetyl CoA-acyl carrier protein S-acyltransferase | <enzyme> Specific for either malonyl-CoA or acetyl-CoA; a component of fatty acid synthase Registry number: EC 2.8.3.- Synonym: mcoa-acoa acp acyltransferase (26 Jun 1999) |
| maltose binding protein | <protein> Protein of the bacterial (E. Coli) surface that links with MCP II and is involved in the chemotactic response to maltose, probably derived from a similar protein that links with a trans membrane transport system. (18 Nov 1997) |
| GCN2 protein kinase | <enzyme> From saccharomyces cerevisiae; has homology to eif-2alpha kinase Registry number: EC 2.7.1.- (26 Jun 1999) |
| ras protein geranylgeranyltransferase | <enzyme> Mammalian enzyme transfers geranylgeranyl groups to a cysteine residue fourth from the c-terminal group of a p21 ras protein, prefers leucine at the cooh terminus; see also rhoa geranylgeranyltransferase and protein geranylgeranyltransferase Registry number: EC 2.5.1.- Synonym: geranylgeranyltransferase ras protein, ras protein gg transferase, ggtase I, caax geranylgeranyl transferase (26 Jun 1999) |
| gene regulatory protein | <molecular biology> Any protein that interacts with DNA sequences of a gene and controls its transcription. (18 Nov 1997) |
| rec A protein | <protein> A protein (40 kD) product of the rec (recombination) gene, that catalyses the pairing of a single stranded piece of DNA with its complementary sequence, displacing a loop of single stranded DNA (D loop). It catalyses the ATP-driven exchange of DNA strands in genetic recombination. The product of the reaction consists of a duplex and a displaced single-stranded loop which has the shape of the letter d and is therefore called a d-loop structure. ATP is hydrolyzed to ADP during the reaction; also has proteolytic activity. (22 Sep 2002) |