| Carrion's disease | A generalised, acute, febrile, endemic, and systemic form of bartonellosis; marked by high fever, rheumatic pains, progressive, severe anaemia, and albuminuria. Synonym: Carrion's disease. (05 Mar 2000) |
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| gestational trophoblastic disease | (choriocarcinoma, molar pregnancy) a type of cancer associated with pregnancy in which a grape-like mole develops in the womb instead of a foetus. (16 Dec 1997) |
| parkinson disease | Progressive, degenerative disease of unknown aetiology characterised by rhythmic tremor of the limbs, stooped posture, slowness of voluntary movements, and masklike facial expression. Pathologically there is nerve cell loss in the melanin-containing cells in the brainstem and a corresponding reduction in dopamine levels in the corpus striatum. Lewy bodies are present in the substantia nigra and locus coeruleus. (12 Dec 1998) |
| parkinson disease, postencephalitic | A form of parkinson disease due to degeneration of the corpus striatum or substantia nigra, frequently occurring as a sequel of lethargic encephalitis. The early age of onset, the rapid progression of symptoms and signs of stabilization, and the presence of a variety of other neurological disorders (sociopathic behaviour, tics, spasms, oculogyric crises and other restricted motor disorders, breathing arrhythmias, hyperphagia, and bizarre movements, postures, and gaits) distinguish this disease from the one described by parkinson. (12 Dec 1998) |
| parkinson disease, symptomatic | Symptoms of parkinson disease induced by drugs, or following cerebral arteriosclerosis, brain tumour, or other central nervous system disorders except encephalitis, which is parkinson disease, postencephalitic. (12 Dec 1998) |
| Parkinson's disease | <neurology> A progressive, neurological disease first described in 1817 by James Parkinson. The pathology is not completely understood, but there appears to be consistent changes in the melanin-containing nerve cells in the brainstem (substantia nigra, locus coeruleus), where there are varying degrees of nerve cell loss with reactive gliosis along with eosinophilic intracytoplasmic inclusions (Lewy bodies). Biochemical studies have shown below normal levels of dopamine in the caudate nucleus and putamen. Symptoms include shuffling gait, stooped posture, resting tremor, speech impediments, movement difficulties and an eventual slowing of mental processes and dementia. (27 Sep 1997) |
| parrot disease | <chest medicine, disease> Psittacosis is primarily an infectious disease of birds caused by the bacterium Chlamydia psittaci. Transmission from infected birds results in a relatively rare febrile illness characterised by pneumonia and systemic symptoms. A flu-like illness can also occur. Almost any bird can harbor this bacterium in their excreta, tissues, feathers and secretions, but parrots, parakeets and budgerigars are the most common. Psittacosis is considered an occupational disease of pet shop owners. Psittacosis is almost always transmitted to humans by the respiratory route. Average incubation is 7-14 days. (27 Sep 1997) |
| Parrot's disease | Pseudoparalysis in infants, due to syphilitic osteochondritis. Synonym: marasmus. (05 Mar 2000) |
| parry's disease | Toxic multinodular goiter. Named for the english physician caleb hillier parry (1755-1822). Also called plummer's disease. (12 Dec 1998) |
| Gierke's disease | Glycogenosis due to glucose-6-phosphatase deficiency, resulting in accumulation of excessive amounts of glycogen of normal chemical structure, particularly in liver and kidney. Synonym: Gierke's disease, glucose-6-phosphatase hepatorenal glycogenosis, von Gierke's disease. (05 Mar 2000) |
| castleman disease | <radiology> Angiofollicular lymph node hyperplasia, benign lymphoid hyperplasia, massively enlarged lymph nodes, mediastinum most common; rarely in mesentery, age less than 30 yrs, types: hyaline vascular (90%), asymptomatic, vascular proliferation and hyalinization, plasma cell (10%), fever, anaemia, increased sed rate, increased IgG (12 Dec 1998) |
| Castleman's disease | Solitary masses of lymphoid tissue containing concentric perivascular aggregates of lymphocytes, occurring usually in the mediastinum or hilar region of young adults; similar changes have been reported outside the mediastinum and, if associated with interfollicular sheets of plasma cells, may progress to lymphoma or plasmacytoma. Synonym: angiofollicular mediastinal lymph node hyperplasia, Castleman's disease. (05 Mar 2000) |
| gilbert's disease | A benign familial disorder, transmitted as an autosomal dominant trait. It is characterised by low-grade chronic hyperbilirubinaemia with considerable daily fluctuations of the bilirubin level. (12 Dec 1998) |
| Gilchrist's disease | <disease> A fungal infection caused by Blastomyces dermatitidis. This rare fungal infection may produce inflammatory lesion of the skin or lungs or present as a disseminated disease to the skin, lungs, bones, liver, spleen and central nervous system. Uncommon unless patient is immunocompromised (AIDS). (27 Sep 1997) |
| Gilles de la Tourette's disease | <syndrome> Both multiple motor and one or more vocal tics present with tics occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or a general medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (dsm-IV, 1994) (12 Dec 1998) |