| tumour suppressor | <molecular biology, oncology> A gene that encodes a product that normally negatively regulates the cell cycle and that must be mutated or otherwise inactivated before a cell can proceed to rapid division. Examples: p53, RB retinoblastoma), WT 1 (Wilm's tumour), DCC (deleted in colonic carcinoma), NF 1 (neurofibrosarcoma) and APC adenomatous polyposis coli). (18 Nov 1997) |
|---|---|
| tumour virus | <oncology, virology> Virus capable of inducing tumours. (18 Nov 1997) |
| tumour viruses, murine | Species of mammalian type c retroviruses (retroviruses type c, mammalian) that cause solid tumours or leukaemias in mice. (12 Dec 1998) |
| tumour virus infections | Infections produced by oncogenic viruses. The infections caused by DNA viruses are less numerous but more diverse than those caused by the RNA oncogenic viruses. (12 Dec 1998) |
| turban tumour | Cylindroma of the scalp which, when overgrown, may resemble a turban. (05 Mar 2000) |
| Ewing's tumour | A malignant primary bone tumour that arises most commonly in the first three decades of life. It is highly malignant (prone to spread) and often requires treatment with some combination of radiation therapy and chemotherapy. (27 Sep 1997) |
| faecal tumour | An accumulation of inspissated faeces in the colon or rectum giving the appearance of an abdominal tumour. Synonym: faecal tumour, fecaloma, scatoma, stercoroma. Origin: copro-+ G. -oma, tumour (05 Mar 2000) |
| yaba monkey tumour virus | The type species of yatapoxvirus, a tumour-producing DNA virus discovered in monkeys in yaba, nigeria. It has been found to produce histiocytomas in monkeys and humans. (12 Dec 1998) |
| Yaba tumour | <oncology, virology> A poxvirus-induced neoplasm of African monkeys caused by the Yaba monkey virus, a member of the family Poxviridae. It is associated with tumour-like growths occur chiefly on the head and limbs. The tumours are benign and the natural disease has been reported only in Africa in monkeys kept outdoors. (05 Mar 2000) |
| yolk sac tumour | An unusual and aggressive tumour of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumour found in children. It is characterised by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (schiller-duval body). The tumour is rarely bilateral. Before the use of combination chemotherapy, the tumour was almost invariably fatal. (12 Dec 1998) |
| kidney tumour | <oncology> A benign or cancerous growth originating from kidney tissue (for example renal cell carcinoma, hypernephroma). (27 Sep 1997) |
| fat necrosis tumour | <surgery> Destruction of fat cells in the breast due to trauma or injury that can cause a hard noncancerous lump. (09 Oct 1997) |
| Zollinger-Ellison tumour | A non-beta cell tumour of pancreatic islets causing the Zollinger-Ellison syndrome. (05 Mar 2000) |
| klatskin's tumour | Adenocarcinoma of the common hepatic duct bifurcation. These tumours are generally small, sharply localised, and seldom metastasizing. G. Klatskin's original review of 13 cases was published in 1965. Once thought to be relatively uncommon, tumours of the bifurcation of the bile duct now appear to comprise more than one-half of all bile duct cancers. (12 Dec 1998) |
| klatskin tumour | <radiology> Tumour at junction of right and left intrahepatic bile ducts, slower growth than usual cholangiocarcinoma, late to metastasize (12 Dec 1998) |