| granulocyte s. |
the succession of morphologically distinguishable cells that are stages in granulocyte development; after the colony-forming unit–granulocyte-macrophage, the stages in order of maturity are the myeloblast, promyelocyte, myelocyte, and metamyelocyte, followed by the band or stab cell, which is the least mature form normally found in the peripheral blood, and the mature segmented (polymorphonuclear) granulocyte. Commitment to one of the granulocyte lines occurs in stem cells before the myeloblast stage, so that there are distinct basophilic, eosinophilic, and neutrophilic series, although all three include the same morphologic stages. Formerly called the myelocytic, myeloid, or leukocytic s.
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| granulocyte-macrophage colony-stimulating f. |
a colony-stimulating factor, secreted by activated T lymphocytes and macrophages and by stimulated endothelial cells, that binds to a specific receptor found on stem cells and most myelocytes and stimulates their differentiation into granulocytes and macrophages. GM-CSF also enhances the function of mature granulocytes and macrophages in vitro. A recombinant form used therapeutically is called sargramostim.
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| granulocytic l. |
myelogenous l.
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| granulocytic s. |
chloroma.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| granulocytopathy |
any disorder of the granular leukocytes (granulocytes).
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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