| benign lymphoepithelial l. |
enlargement of the salivary glands, which sometimes become tender, with infiltration of the parenchyma by polyclonal B cells and T cells, atrophy of acini, and formation of lymphoepithelial islands; usually seen in middle-aged women associated with Sjögren syndrome, but also seen in a number of collagen disorders. The lesion is usually benign but may be associated with non-Hodgkin lymphoma. Called also Mikulicz disease (particularly when there is lacrimal gland enlargement) and benign lymphoepithelial sialadenopathy.
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| benign lymphoepithelial s. |
see under lesion.
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| benign m. |
a benign tumor composed of two or more clearly recognizable mesenchymal elements in addition to fibrous tissue.
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| benign migratory g. |
a type with unknown etiology, characterized by annular areas of desquamation of the filiform papillae on the dorsal surface of the tongue, usually presenting pinkish-red central lesions outlined by thin, yellowish lines or bands that change patterns and shift location every few days. Called also g. areata exfoliativa, g. migrans, erythema migrans, geographic tongue, and pityriasis linguae.
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| benign monoclonal g. |
the presence of a serum M component without signs or symptoms of multiple myeloma, Waldenström's macroglobulinemia, or other plasma cell neoplasms; it occurs in about 3 per cent of the population over age 70. A few patients eventually develop a malignant plasma cell dyscrasia. Called also monoclonal g. of undetermined significance.
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