| myosin heavy chains | The heavy chains of the muscle protein myosin. Each molecule of myosin is composed of two heavy chains and two pairs of light chains. The heavy chains have a molecular weight of about 230 kD and each heavy chain is associated with a dissimilar pair of light chains. (devlin, textbook of biochemistry: with clinical correlations, 3rd ed, p957) (12 Dec 1998) |
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| myosin light chain | <protein> The light chains of the muscle protein myosin. Each molecule of myosin is composed of two heavy chains and two pairs of light chains. The light chains have a molecular weight of about 20 kD and there is one dissimilar pair of light chains associated with each heavy chain. The proteins all have sequence homology to calmodulin, but not all with calcium binding activity. Several types are known: regulatory light chains (LC 2, DNTB light chains) probably regulate the ATPase activity of the heavy chain directly (through the binding of calcium) or indirectly (activating when they themselves are phosphorylated by myosin light chain kinase) and essential light chains (LC 1, LC 3, alkali light chains), which have a more subtle and apparently nonessential role. In molluscan muscle the EDTA light chains (similar to LC 2 from vertebrate muscle) confer calcium sensitivity on the myosin itself. The light chains are "calmodulin-like" proteins that bind calcium. Two of them can be removed easily, and two with difficulty. The light chains bind the heavy chains in the vicinity of the head groups of the myosin. (12 Dec 1998) |
| myosin light chain kinase | <enzyme> An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and calmodulin. The 20-kD light chain is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors. The enzyme plays a central role in the regulation of smooth muscle contraction. Chemical name: ATP:myosin-light-chain O-phosphotransferase Registry number: EC 2.7.1.117 (12 Dec 1998) |
| myosin subfragments | Parts of the myosin molecule resulting from cleavage by proteolytic enzymes (papain, trypsin, or chymotrypsin) at well-localised regions. Study of these isolated fragments helps to delineate the functional roles of different parts of myosin. Two of the most common subfragments are myosin s-1 and myosin s-2. S-1 contains the heads of the heavy chains plus the light chains and s-2 contains part of the double-stranded, alpha-helical, heavy chain tail (myosin rod). (12 Dec 1998) |
| myosinogen | Proteins extracted from muscle with cold water, largely the enzymes promoting glycolysis; from the residue, alkaline 0.6 m KCl extracts actin and myosin as actomyosin, with myosin further separable into two meromyosins by proteinase treatment. Synonym: myosinogen. Origin: myo-+ G. -gen, producing (05 Mar 2000) |
| myosinose | A proteose formed by the partial hydrolysis of myosin. (05 Mar 2000) |
| myosis | <medicine> Long-continued contraction of the pupil of the eye. Origin: NL, fr. Gr. To close the eyes or lips. Source: Websters Dictionary (01 Mar 1998) |
| myositic | <medicine> Myotic. Source: Websters Dictionary (01 Mar 1998) |
| myositis | <pathology> Inflammation of a voluntary muscle. Origin: Gr. Myos = of muscle (18 Nov 1997) |
| myositis fibrosa | Induration of a muscle through an interstitial growth of fibrous tissue. Synonym: Froriep's induration, interstitial myositis, myofascitis. (05 Mar 2000) |
| myositis ossificans | A disease characterised by bony deposits or the ossification of muscle tissue. (12 Dec 1998) |
| myositis ossificans circumscripta | Local deposit of bone in a muscle, usually following prolonged trauma; e.g., riders' bone. (05 Mar 2000) |
| myositis ossificans progressiva | <radiology> Progressive skeletal fusion, ossification of ligaments, nuchal ligament, pelvic entheses, asymptomatic at birth, 90% have short great toes (12 Dec 1998) |
| myositis purulenta tropica | A disease observed in Samoa and in tropical Africa, marked by pains in the extremities, fever of a remittent or intermittent type, and abscesses in the muscles in various parts of the body (may result in death from sepsis); causative organisms are Staphylococcus aureus and Streptococcus pyogenes, but usually the disease is associated with parasitic infections. Synonym: bungpagga, lambo lambo, tropical myositis, tropical pyomyositis. (05 Mar 2000) |
| myositis, inclusion body | A progressive inflammatory myopathy primarily involving muscles of the pelvic region and legs, usually seen in older people. The muscles are infiltrated by mononuclear inflammatory cells, sarcoplasmic vacuoles, masses of filaments and filamentous microtubules, and sometimes eosinophilic bodies. (12 Dec 1998) |
| myomectomy |
In patients with idiopathic hypertrophic subaortic stenosis (IHSS) also known as hypertrophic obstructive cardiomyopathy (HOCM) one surgical option is to perform a myomectomy which is a resection of a thickened portion of the muscular septum thereby relieving the obstruction to blood flow in the left ventricle during contraction.
출처: www.clevelandclinic.org/heartcenter/pub/glossary/m...
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| myotonic dystrophy |
an inherited (autosomal dominant) neuromuscular disorder that occurs in adults, characterized by progressive muscle weakness and wasting and myotonia; onset is usually in the third decade
출처: depts.washington.edu/pwdlearn/web/glossary/glossar...
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| myopathy |
progressive muscle weakness. Myopathy may arise as a toxic reaction to AZT (ZIDOVUDINE) or as a consequence of HIV infection itself.
출처: www.gmhc.org/health/glossary3.html
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| myocardial |
refers to the heart's muscle mass.
출처: www.gmhc.org/health/glossary3.html
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| myopathic |
a muscle problem
출처: www.vh.org/pediatric/patient/cancercenter/bannayan...
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