| monocyte chemotactic and activating factor | Cytokine of the C C subfamily, co induced with IL-8 on stimulation of endothelial cells, fibroblasts or monocytes that activates and is chemotactic for, monocytes. A chemokine. (18 Nov 1997) |
|---|---|
| monocyte derived neutrophil chemotactic factor | <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4. Acronym: IL-8 (12 Dec 1998) |
| monocytes | One of three types of white blood cells. Monocytes are precursors to macrophages. (14 Nov 1997) |
| monocytes, activated killer | Monocytes made cytotoxic by ex vivo incubation with cytokines, especially interferon-gamma. Akm cells are used for adoptive immunotherapy in cancer patients. (12 Dec 1998) |
| monocytic angina | An obsolete term for infectious mononucleosis. (05 Mar 2000) |
| monocytic leukaemia | Cancer of the blood due to proliferation of cells of the monocyte series. Origin: Gr. Haima = blood (13 Nov 1997) |
| monocytic leukemoid reaction | Leukocytosis of varying degree, e.g., 30,000 to 40,000 per cu mm, with adult monocytes and immature forms amounting to 30% (or more) of the total number of white blood cells in the circulating blood; may be observed in association with tuberculosis, especially the first infection, miliary type. (05 Mar 2000) |
| monocytic leukocytosis | An abnormal increase in the number of monocytes in the circulating blood. Synonym: monocytic leukocytosis. (05 Mar 2000) |
| monocytic leukopenia | Diminution in the number of monocytes in the circulating blood. Synonym: monocytic leukopenia, monopenia. Origin: mono-+ G. Kytos, cell, + penia, poverty (05 Mar 2000) |
| monocytoid cell | A cell having morphological characteristics of a monocyte but which is nonphagocytic. (05 Mar 2000) |
| monocytopenia | Diminution in the number of monocytes in the circulating blood. Synonym: monocytic leukopenia, monopenia. Origin: mono-+ G. Kytos, cell, + penia, poverty (05 Mar 2000) |
| monocytosis | An abnormal increase in the number of monocytes in the circulating blood. Synonym: monocytic leukocytosis. (05 Mar 2000) |
| Monod | Jacques L., French biochemist and Nobel laureate, 1910-1976. See: Monod-Wyman-Changeux model. (05 Mar 2000) |
| Monod-Wyman-Changeux model | A model used to explain the allosteric form of cooperativity; in this model, an oligomeric protein can exist in two conformational states in the absence of the ligand; these states are in equilibrium and the one that is predominant has a lower affinity for the ligand (which binds to the protein in a rapid equilibrium fashion). Synonym: concerted model. (05 Mar 2000) |
| monodactylous | <zoology> Having but one finger or claw. Origin: Gr.; single + finger: cf. F. Monodactyle. Source: Websters Dictionary (01 Mar 1998) |