| antibody deficiency disease | <syndrome> Any of a group of disorders associated with a defective antibody production due to defects in the B-type lymphocyte system or in T-type lymphocytes; chief manifestation is an increased susceptibility to infection by various microorganisms. See: agammaglobulinaemia, hypogammaglobulinaemia, immunodeficiency. Synonym: antibody deficiency disease. (05 Mar 2000) |
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| anti-glomerular basement membrane disease | Glomerulonephritis, usually of a generalised proliferative crescent-forming histologic type with a rapidly progressive course, marked by circulating anti-gbm antibodies and linear deposits of immunoglobulin and complement along the glomerular basement membrane. When associated with pulmonary haemorrhage the condition is called goodpasture syndrome. (12 Dec 1998) |
| aortoiliac occlusive disease | Obstruction of the abdominal aorta and its main branches by atherosclerosis. (05 Mar 2000) |
| apical interstitial lung disease | <radiology> A radiological diagnosis where fibrosis is seen in the apices (upper sections) of the lungs. Likely causes include: cystic fibrosis, ankylosing spondylitis, sarcoidosis, silicosis, eosinophlic granuloma, TB and fungus, particularly aspergillus infection. (25 Jun 1999) |
| Aran-Duchenne disease | A serious neurologic disease that results from the progressive degeneration of the motor neurons. (27 Sep 1997) |
| asbestos lung disease | <radiology> Pleural plaques, earliest finding, may be only evidence, parietal pleura, 15-20 yrs after exposure, calcified after ca. 30 yrs, asbestosis, interstitial lung disease, perihilar regions to lung bases, shaggy heart, no cavitation or progressive massive fibrosis as in silicosis, crocidolite (blue) form most carcinogenic, associated with: malignant pleural mesothelioma, peritoneal mesothelioma, GI-tract malignancy (12 Dec 1998) |
| asherman disease | <radiology> Uterine synechiae, linear, lucent defects in uterus on HSG, usually secondary to endometrial trauma (D&C, etc.) (12 Dec 1998) |
| atherosclerotic vascular disease | <cardiology> The progressive narrowing and hardening of the arteries over time. This is known to occur to some degree with aging, but other risk factors that accelerate this process have been identified. These factors include: high cholesterol, high blood pressure, smoking, diabetes and family history for atherosclerotic disease. (27 Sep 1997) |
| Aujeszky's disease | A highly contagious herpes virus infection affecting the central nervous system of swine, cattle, dogs, cats, rats, and other animals. (12 Dec 1998) |
| Aujeszky's disease virus | A herpesvirus causing pseudorabies in swine. Synonym: Aujeszky's disease virus. (05 Mar 2000) |
| Australian X disease | A severe encephalitis with a high mortality rate occurring in the Murray Valley of Australia; the disease is most severe in children and is characterised by headache, fever, malaise, drowsiness or convulsions, and rigidity of the neck; extensive brain damage may result; it is caused by the Murray Valley encephalitis virus (genus Flavivirus). Synonym: Australian X disease, Australian X encephalitis. (05 Mar 2000) |
| Australian X disease virus | A group B arbovirus of the genus Flavivirus that causes Murray Valley encephalitis; it is transmitted by Culex mosquitoes, and also infects birds and horses. Synonym: Australian X disease virus, MVE virus. (05 Mar 2000) |
| autoimmune disease | <disease> A disease process that involves the production of host antibodies to host tissue. (27 Sep 1997) |
| aviator's disease | Syndrome resembling decompression sickness occurring in occupants of airplanes that reach very high altitudes without adequate pressurization of the cabin. See: decompression sickness. (05 Mar 2000) |
| Ayerza's disease | <syndrome> Sclerosis of the pulmonary arteries in chronic cor pulmonale; associated with severe cyanosis, it is a condition resembling polycythemia vera but resulting from primary pulmonary arteriosclerosis or primary pulmonary hypertension and characterised by plexiform lesions of arterioles. Synonym: Ayerza's disease, cardiopathia nigra, plexogenic pulmonary arteriopathy. (05 Mar 2000) |