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α-aminoadipate the anionic form of α-aminoadipic acid.
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α-aminoadipic acid a dicarboxylic amino acid occurring as an intermediate in the degradation of lysine and hydroxylysine. Written also 2-aminoadipic acid.
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α-aminoadipic semialdehyde synthase a bifunctional enzyme comprising the two enzyme activities saccharopine dehydrogenase (NADP+, L-lysine-forming) (q.v.) and saccharopine dehydrogenase (NAD+, L-glutamate-forming) (q.v.) and catalyzing the first two steps in the major pathway of lysine degradation. Deficiency of the enzyme, an autosomal recessive trait, causes hyperlysinemia. See also saccharopinuria.
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α-aminoadipicaciduria excretion of α-aminoadipic acid in the urine.
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α1-antitrypsin alpha1-antitrypsin.
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