| lymphoma | <oncology, tumour> Malignant tumour of lymphoblasts derived from B lymphocytes. most commonly affects children in tropical Africa: both Epstein Barr virus and immunosuppression due to malarial infection are involved. (18 Nov 1997) |
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| lymphoma, aids-related | B-cell lymphoid tumours that occur in association with aids. Patients often present with an advanced stage of disease and highly malignant subtypes including burkitt lymphoma, immunoblastic large-cell lymphoma, small non-cleaved-cell lymphoma and diffuse large-cell lymphoma. The tumours are often disseminated in unusual extranodal sites and chromosomal abnormalities are frequently present. It is likely that polyclonal B-cell lymphoproliferation in aids is a complex result of ebv infection, HIV antigenic stimulation, and T-cell-dependent HIV activation. (12 Dec 1998) |
| lymphoma, B-cell | A group of heterogeneous lymphoid tumours generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes. (12 Dec 1998) |
| lymphoma, diffuse | Malignant lymphoma in which neoplastic cells diffusely infiltrate the entire lymph node without any definite organised pattern. Patients whose lymphomas present a diffuse pattern generally have a more unfavorable survival outlook than those presenting with a follicular or nodular pattern. (12 Dec 1998) |
| lymphoma, follicular | Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the lymph nodes. The nodules resemble to some extent the germinal centres of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular centre B-lymphocytes. This class of lymphoma usually occurs in older persons, is commonly multinodal, and possibly extranodal. Patients whose lymphomas present a follicular or nodular pattern generally have a more indolent course than those presenting with a diffuse pattern. (12 Dec 1998) |
| lymphoma, high-grade | One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have a relatively unfavorable survival potential. (12 Dec 1998) |
| lymphoma, intermediate-grade | One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have an intermediate survival potential. (12 Dec 1998) |
| lymphoma, large-cell | A form of malignant lymphoma in which the malignant cells resemble histiocytes morphologically but are presently considered to be derived from lymphoid elements. These cells are irregular in shape with relatively abundant, frequently acidophilic cytoplasm. Large-cell lymphoma can occur in both nodular (follicular) and diffuse forms, with the latter being more frequently seen. (12 Dec 1998) |
| lymphoma, large-cell, diffuse | Malignant lymphoma composed of large cells which may be both cleaved and noncleaved. The pattern is predominantly diffuse. most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation. (12 Dec 1998) |
| lymphoma, large-cell, follicular | Malignant lymphoma in which the majority of neoplastic cells within the follicles are large cleaved or noncleaved cells. The degree to which the follicular centre cells retain their ability to form follicles varies with the state of B-cell transformation. (12 Dec 1998) |
| lymphoma, large-cell, immunoblastic | Malignant lymphoma characterised by the presence of immunoblasts with uniformly round-to-oval nuclei, one or more prominent nucleoli, and abundant cytoplasm. This class may be subdivided into plasmacytoid and clear-cell types based on cytoplasmic characteristics. A third category, pleomorphous, may be analogous to some of the peripheral T-cell lymphomas (lymphoma, T-cell, peripheral) recorded in both the united states and japan. (12 Dec 1998) |
| lymphoma, large-cell, ki-1 | A large-cell, non-hodgkin's, malignant lymphoma with pleomorphic appearance and reactivity with the monoclonal antibody ki-1. The lymphoma is most often found in the skin and lymph nodes and expresses the ki-1 (CD30) antigen (antigens, CD30) on its surface. It is often mistaken for metastatic carcinoma and malignant histiocytosis. (12 Dec 1998) |
| lymphoma, low-grade | One of the three major prognostic groupings for non-hodgkin lymphomas as proposed in the working formulation of the non-hodgkin's lymphoma pathologic classification project sponsored by the national cancer institute (1981). Lymphomas falling within this group have a relatively favourable survival potential. (12 Dec 1998) |
| lymphoma, lymphoblastic | A high-grade malignant lymphoma composed of a diffuse, relatively uniform proliferation of cells with round or convoluted nuclei and scanty cytoplasm. The cells are cytologically similar to the lymphoblasts seen in acute lymphocytic leukaemia, and in some cases, the disease may evolve into a leukaemic phase morphologically indistinguishable from acute t-lymphocytic leukaemia (leukaemia, T-cell, acute). Lymphoblastic lymphoma represents approximately one-third of the cases of non-hodgkin's lymphomas in children and 5% of the cases in adults. It is more prevalent in males. (12 Dec 1998) |
| lymphoma, mixed-cell | Malignant lymphoma characterised by the presence of a mixed population of cells, with the smaller cells resembling lymphocytes and the larger ones histiocytes. It usually presents in a nodular (follicular) pattern, but may evolve into a diffuse pattern. (12 Dec 1998) |
Synonyms : Diffuse Small Cleaved-Cell Lymphoma, Lymphoma, Small Cleaved Cell, Diffuse, Small Cleaved-Cell Lymphoma, Diffuse, Diffuse Small Cleaved Cell Lymphoma, Small Cleaved Cell Lymphoma, Diffuse
Synonyms : Lymphocytic Lymphoma, Nodular, Poorly Differentiated, Lymphoma, Lymphocytic, Nodular, Poorly Differentiated, Lymphoma, Small Cleaved Cell, Follicular, Small Cleaved-Cell Lymphoma, Follicular, Small Follicular Center-Cell Lymphoma
Synonyms : Diffuse Well-Differentiated Lymphocytic Lymphoma, Lymphocytic Lymphoma, Diffuse, Well Differentiated, Lymphocytic Lymphoma, Well Differentiated, Lymphoma, Lymphocytic, Diffuse, Well Differentiated, Lymphoma, Lymphocytic, Well Differentiated
Synonyms : Diffuse Undifferentiated Lymphoma, Lymphoma, Small Non-Cleaved-Cell, Small Non-Cleaved-Cell Lymphoma, Small Noncleaved-Cell Lymphoma, Diffuse Undifferentiated Lymphomas, Lymphoma, Diffuse Undifferentiated, Lymphoma, Small Non Cleaved Cell
Synonyms : Small-Cell Lymphoma, Lymphocytic Lymphomas, Lymphoma, Small Cell, Lymphomas, Lymphocytic, Lymphomas, Small-Cell, Small Cell Lymphoma, Small-Cell Lymphomas
| lymph node |
a small gland that is part of the immune system; contains white blood cells and antibodies and helps fight against the spread of infection
Ãâó: www.american-depot.com/services/resources_gl_l.asp
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| lymph- |
a milky fluid containing white blood cells, proteins, and fats; plays an important role in absorbing fats from the intestine and in the functioning of the immune system
Ãâó: www.american-depot.com/services/resources_gl_l.asp
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| lymphogranuloma venereum |
a sexually transmitted chlamydial infection; common in countries with a tropical climate
Ãâó: www.american-depot.com/services/resources_gl_l.asp
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| lymphomas |
a group of cancer of the lymph nodes and spleen that can spread to other parts of the body
Ãâó: www.american-depot.com/services/resources_gl_l.asp
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| lymphangiectasia |
Dilation of the lymphatic vessels that is caused by lymphatic damage, which leads to the blockage of local lymphatic drainage.
Ãâó: www.nature.com/nrg/journal/v4/n12/glossary/nrg1225...
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