| immunophilin | <protein> Generic term for intracellular protein that binds immunosuppressive drugs such as cyclosporin, FK506, rapamycin. Both cyclophilin and the receptor for FK506 are peptidyl prolyl cis trans isomerases rotamases). Immunophilins are thought to interact with calcineurin. (18 Nov 1997) |
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| immunopotentiation | Enhancement of the immune response by increasing its rate or prolonging its duration. (05 Mar 2000) |
| immunopotentiator | Any of a wide variety of specific or non-specific substances which on inoculation enhances or augments an immune response. (05 Mar 2000) |
| immunoprecipitation | <immunology> The precipitation of a multivalent antigen by a bivalent antibody, resulting in the formation of a large complex. The antibody and antigen must be soluble. Precipitation usually occurs when there is near equivalence between antibody and antigen concentrations. (18 Nov 1997) |
| immunoproliferative disorders | Disorders characterised by abnormal proliferation of primary cells of the immune system or by excessive production of immunoglobulins. (12 Dec 1998) |
| immunoproliferative small intestinal disease | A spectrum of conditions ranging from a benign plasma cell hyperplasia to a highly malignant lymphoma of the small intestine. (12 Dec 1998) |
| immunoproteins | Blood proteins whose activities affect or play a role in the functioning of the immune system. (12 Dec 1998) |
| immunoradiometric assay | <immunology> A test that measures the concentration of antigens in a specimen throughserological analysis that involves mixing radioactive antibodies with the antigen in question. (09 Oct 1997) |
| immunoreaction | An immunologic reaction, especially in vitro between antigen and antibody. (05 Mar 2000) |
| immunoreactive | Denoting or exhibiting immunoreaction. (05 Mar 2000) |
| immunoregulation | <immunology> The various processes by which antibodies may regulate immune responses. at a simple level, secreted antibody neutralises the antigen with which it reacts thus preventing further antigenic stimulation of the antibody producing clone. at a more complex level, anti-idiotype antibodies can be shown to develop against the first antibodies in some cases and perhaps further anti-idiotype antibodies against them. This is the major concept of the immunological network theory. (18 Nov 1997) |
| immunoselection | 1. Selective death or survival of foetuses of different genotypes depending on immunologic incompatibility with the mother. 2. The survival of certain cells depending on their surface antigenicity. (05 Mar 2000) |
| immunosensors | An antibody that serves as the biological component of a biosensor. Biosensors typically have a biological component and a detection component. The biological component confers selectivity on the sensor, and the detection component turns it into a recognisable 'signal.' Immunosensors detect the tiny changes in mass that occur when an antibody binds to an antigen. (14 Nov 1997) |
| immunosorbent | An antibody (or antigen) used to remove specific antigen (or antibody) from solution or suspension; commonly used with reference to antibody bound to a particulate substance such as a dextran polymer used to remove soluble antigen (e.g., insulin) from solution. (05 Mar 2000) |
| immunosorbent techniques | Techniques for removal by adsorption and subsequent elution of a specific antibody or antigen using an immunosorbent containing the homologous antigen or antibody. (12 Dec 1998) |